EP 1001805 A1 20000524 - METHODS FOR IDENTIFYING ANTIBODIES AND PEPTIDES USEFUL IN THE TREATMENT OF SEPTIC SHOCK AND EXPERIMENTAL ARTHRITIS AND USES THEREOF
Title (en)
METHODS FOR IDENTIFYING ANTIBODIES AND PEPTIDES USEFUL IN THE TREATMENT OF SEPTIC SHOCK AND EXPERIMENTAL ARTHRITIS AND USES THEREOF
Title (de)
VERFAHREN ZUR IDENTIFIZIERUNG VON ANTIKÖRPERN UND PEPTIDEN FÜR DIE BEHANDLUNG VON SEPTISCHEN SCHOCK UND EXPERIMENTELLER ARTHRITIS UND VERWENDUNGEN
Title (fr)
PROCEDES D'IDENTIFICATION D'ANTICORPS ET DE PEPTIDES UTILES DANS LE TRAITEMENT DU CHOC SEPTIQUE ET DE L'ARTHRITE EXPERIMENTALE; UTILISATION DE CES DERNIERS
Publication
Application
Priority
- US 9812647 W 19980617
- US 87798897 A 19970618
- US 5008797 P 19970618
- US 9783898 A 19980616
Abstract (en)
[origin: WO9857657A1] The present invention teaches the use of antibodies raised against the Group A mucopeptide for the treatment of septic shock and Rheumatoid Arthritis, and the identification of specific peptides that can be used in such treatments. The invention includes methods of using the antibodies raised against the Group A mucopeptide including as a means identifying specific peptides, the specificpeptides themselves, and methods of using the peptides. In certain embodiments, the specific peptides serve as mimics to these antibodies. Such peptides can be administered to an animal subject to block the microbial action that initiates Rheumatoid Arthritis via tumor necrosis factor. Alternatively, specific peptides of the present invention can be used to immunize Rheumatoid Arthritis-susceptible individuals to prevent further progression of the diseases. In still other embodiments, the peptides serve as binding partners for these antibodies.
IPC 1-7
IPC 8 full level
G01N 33/53 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01); A61P 9/02 (2006.01); A61P 19/02 (2006.01); A61P 29/00 (2006.01); A61P 31/04 (2006.01); A61P 37/00 (2006.01); C07K 9/00 (2006.01); C07K 14/47 (2006.01); C07K 16/12 (2006.01); C07K 16/28 (2006.01); G01N 33/564 (2006.01); G01N 33/68 (2006.01)
CPC (source: EP)
A61P 9/02 (2017.12); A61P 19/02 (2017.12); A61P 29/00 (2017.12); A61P 31/04 (2017.12); A61P 37/00 (2017.12); C07K 9/00 (2013.01); C07K 16/12 (2013.01); G01N 33/564 (2013.01); G01N 33/68 (2013.01); A61K 38/00 (2013.01); G01N 2333/195 (2013.01)
Citation (search report)
See references of WO 9857657A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9857657 A1 19981223; AU 730308 B2 20010301; AU 7975398 A 19990104; CA 2295440 A1 19981223; EP 1001805 A1 20000524; JP 2002516634 A 20020604
DOCDB simple family (application)
US 9812647 W 19980617; AU 7975398 A 19980617; CA 2295440 A 19980617; EP 98930343 A 19980617; JP 50476899 A 19980617