Global Patent Index - EP 1001953 A1

EP 1001953 A1 2000-05-24 - CRISTALLINE ( - ) - 3R,4R -TRANS-7-METHOXY -2,2-DIMETHYL-3-PHENYL-4- 4- 2-(PYRROLIDIN-1-YL)ETHOXY PHENYL CHROMANE, HYDROGEN MALEATE

Title (en)

CRISTALLINE ( - ) - 3R,4R -TRANS-7-METHOXY -2,2-DIMETHYL-3-PHENYL-4- 4- 2-(PYRROLIDIN-1-YL)ETHOXY PHENYL CHROMANE, HYDROGEN MALEATE

Title (de)

KRISTALLINES ( - ) - 3R,4R -TRANS-7-METHOXY -2,2-DIMETHYL-3-PHENYL-4-¬4- 2-(PYRROLIDIN-1-YL)ETHOXY PHENYLCHROMAN-HYDROGENMALEAT

Title (fr)

( - ) - 3R,4R -TRANS-7-METHOXY -2,2-DIMETHYL-3-PHENYL-4- 4- 2-(PYRROLIDINE-1-YL)ETHOXY PHENYL CHROMANE CRISTALLISE, MALEATE D'HYDROGENE

Publication

EP 1001953 A1 (EN)

Application

EP 98929224 A

Priority

  • DK 9800244 W
  • DK 69297 A
  • US 5019297 P

Abstract (en)

[origin: WO9856782A1] The present invention provides novel crystalline ( - ) - 3R,4R -trans-7-methoxy -2,2-dimethyl-3-phenyl-4- {4-[2-(pyrrolidin-1-yl)ethoxyl] phenyl}chromane, hydrogen maleate useful for reducing or preventin bone loss as well as pharmaceutical compositions containing the same. A process for preparing ( - ) - 3R,4R -trans-7-methoxy-2,2-dimethyl-3-phenyl-4-{4-[2-(pyrrolidin-1-yl)ethoxy]phenyl}chromane, hydrogen maleate is described.

IPC 1-7 (main, further and additional classification)

C07D 311/58; A61K 31/35; A61K 31/40

IPC 8 full level (invention and additional information)

C07D 311/58 (2006.01)

CPC (invention and additional information)

C07D 311/58 (2013.01)

Citation (search report)

See references of WO 9856782A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9856782 A1 19981217; AU 7906498 A 19981230; EP 1001953 A1 20000524

INPADOC legal status


2007-11-14 [RTI1] TITLE (CORRECTION)

- Free text: CRISTALLINE ( - ) - 3R,4R -TRANS-7-METHOXY -2,2-DIMETHYL-3-PHENYL-4- 4- 2-(PYRROLIDIN-1-YL)ETHOXY PHENYL CHROMANE, HYDROGEN MALEATE

2003-10-22 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030423

2001-05-16 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010402

2000-05-24 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000112

2000-05-24 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE