Global Patent Index - EP 1001989 A1

EP 1001989 A1 2000-05-24 - PROLACTIN SECRETION MODULATOR

Title (en)

PROLACTIN SECRETION MODULATOR

Title (de)

PROLAKTIN SEKRETIONSMODULATOR

Title (fr)

MODULATEUR DE SECRETION DE PROLACTINE

Publication

EP 1001989 A1 (EN)

Application

EP 98928607 A

Priority

  • JP 9802765 W
  • JP 16543797 A

Abstract (en)

[origin: WO9858962A1] The present invention relates to a ligand polypeptide prolactin secretion modulating activity, and has a function of modulating placental function. The ligand polypeptide can be used as a prolactin secretion-stimulating agent for the prevention and treatment of certain diseases associated with prolactin secretion, such as hypoovarianism, gonecyst cacogenesis, menopausal syndrome, and euthyroid hypometabolism. In addition, the ligand polypeptide of the invention can be used with advantage as an aphrodisiac. The ligand polypeptide of the invention can be used with advantage as a prolactin secretion inhibitory agent in the prevention and treatment of certain diseases associated with prolactin secretion, such as pituitary adenomatosis, brain tumor, emmeniopathy, autoimmune disease, prolactinoma, infertility, impotence, amenorrhea, galactorrhea, acromegaly, Chiari-Frommel syndrome, Argonz-del Castilo syndrome, Forbes-Albright syndrome, lymphoma, Sheehan syndrome or dyszoospermia. In addition, the ligand polypeptide of the present invention is used as an agent for treating or preventing chriocarcinomia, hydatid mole, irruption mole, abortion, unthrifty fetus, abnormal saccharometabolism, abnormal lipidmetabolism or oxytocia.

IPC 1-7 (main, further and additional classification)

C07K 14/575; A61K 38/22; C07K 14/72; C07K 16/26; C12N 15/16; G01N 33/74

IPC 8 full level (invention and additional information)

C07K 14/575 (2006.01); C07K 14/72 (2006.01); C12N 15/16 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

C07K 14/575 (2013.01); C07K 14/723 (2013.01); A61K 38/00 (2013.01)

Citation (search report)

See references of WO 9858962A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9858962 A1 19981230; AU 8037398 A 19990104; CA 2295210 A1 19981230; EP 1001989 A1 20000524

INPADOC legal status


2006-06-14 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20051215

2004-12-22 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: TAKEDA PHARMACEUTICAL COMPANY LIMITED

- Ref Legal Event Code: RAP1

2003-08-13 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20030626

2000-05-24 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19991209

2000-05-24 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE