Global Patent Index - EP 1002073 A2

EP 1002073 A2 2000-05-24 - CELL ACTIVATION PROCESS AND REAGENTS THEREFOR

Title (en)

CELL ACTIVATION PROCESS AND REAGENTS THEREFOR

Title (de)

VERFAHREN UND REAGENZIEN ZUR AKTIVIERUNG VON ZELLEN

Title (fr)

PROCEDE D'ACTIVATION DE CELLULE ET REACTIFS A CET EFFET

Publication

EP 1002073 A2 (EN)

Application

EP 98930934 A

Priority

  • GB 9801842 W
  • GB 9713473 A

Abstract (en)

[origin: WO9900494A2] A cell activation process is described in which an effector cell is transformed with DNA coding for a chimeric receptor containing two or more different cytoplasmic signalling components. At least one of the cytoplasmic signalling components is derived from all or part of a tetraspan-transmembrane protein, CD43, CD6, a mannose, IL-7, IL-12 or complement receptor, an integrin-associated protein, or a gamma -chain associated with a cytokine receptor. The activated cell may be of use in medicine for example in the treatment of diseases such as cancer.

IPC 1-7 (main, further and additional classification)

C12N 15/12; A61K 48/00; C07K 14/705; C07K 14/715; C07K 14/735; C07K 16/28; C07K 19/00; C12N 5/10; C12N 9/12; C12N 15/13; C12N 15/54; C12N 15/62; G01N 33/58; G01N 33/68

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 9/127 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); A61P 43/00 (2006.01); C07K 14/705 (2006.01); C07K 14/715 (2006.01); C07K 14/725 (2006.01); C07K 14/73 (2006.01); C07K 14/735 (2006.01); C07K 16/28 (2006.01); C07K 19/00 (2006.01); C12N 5/10 (2006.01); C12N 9/12 (2006.01); C12N 15/12 (2006.01)

CPC (invention and additional information)

C12N 9/1205 (2013.01); C07K 14/705 (2013.01); C07K 14/70503 (2013.01); C07K 14/70507 (2013.01); C07K 14/7051 (2013.01); C07K 14/70514 (2013.01); C07K 14/70517 (2013.01); C07K 14/70521 (2013.01); C07K 14/70525 (2013.01); C07K 14/70535 (2013.01); C07K 14/70596 (2013.01); C07K 14/715 (2013.01); C07K 14/7155 (2013.01); C07K 16/2896 (2013.01); A61K 48/00 (2013.01); C07K 2319/00 (2013.01); C07K 2319/02 (2013.01); C12N 2799/021 (2013.01)

Citation (search report)

See references of WO 9900494A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9900494 A2 19990107; WO 9900494 A3 19990325; AU 8121098 A 19990119; EP 1002073 A2 20000524; GB 9713473 D0 19970903; JP 2002511757 A 20020416

INPADOC legal status


2006-10-04 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20060411

2004-09-08 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040723

2000-05-24 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000113

2000-05-24 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE