EP 1002119 A1 20000524 - TARGETED HSV VECTORS
Title (en)
TARGETED HSV VECTORS
Title (de)
ZIELGERICHTETE HSV-VEKTOREN
Title (fr)
VECTEURS DE VIRUS D'HERPES SIMPLEX (HSV) CIBLES
Publication
Application
Priority
- US 9816051 W 19980731
- US 5432997 P 19970731
Abstract (en)
[origin: WO9906583A1] The present invention relates to targeting HSV vectors, chiefly by modifying viral proteins. Thus, the present invention provides an HSV having an envelope which includes a non-native ligand. For targeting the HSV vector to a specific cell type, the non-native ligand is typically a cell-surface ligand. Additionally, for altering the native broad targeting of HSV vectors, the targeted HSV can lack a native cell-surface ligand.
IPC 1-7
IPC 8 full level
C12N 15/869 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
C12N 15/86 (2013.01); A61K 48/00 (2013.01); C12N 2710/16643 (2013.01)
Citation (search report)
See references of WO 9906583A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9906583 A1 19990211; AU 8605598 A 19990222; EP 1002119 A1 20000524
DOCDB simple family (application)
US 9816051 W 19980731; AU 8605598 A 19980731; EP 98937316 A 19980731