Global Patent Index - EP 1003374 A1

EP 1003374 A1 20000531 - INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (en)

INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE

Title (de)

INHIBITOREN VON FARNESYL-PROTEIN-TRANSFERASE

Title (fr)

INHIBITEURS DE FARNESYL-PROTEINE TRANSFERASE

Publication

EP 1003374 A1 (EN)

Application

EP 97954798 A

Priority

  • GB 9702212 A
  • US 9723888 W
  • US 3399196 P

Abstract (en)

[origin: WO9828980A1] The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and the farnesylation of the oncogene protein Ras.

IPC 1-7

A01N 43/40; A01N 43/54; A01N 43/58; C07D 401/00; C07D 401/06; C07D 401/14; A61K 31/44

IPC 8 full level

A61K 31/4439 (2006.01); A61K 31/497 (2006.01); A61K 31/506 (2006.01); A61P 9/00 (2006.01); A61P 13/12 (2006.01); A61P 27/02 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01)

CPC (source: EP)

A61P 9/00 (2018.01); A61P 13/12 (2018.01); A61P 27/02 (2018.01); A61P 35/00 (2018.01); A61P 43/00 (2018.01); C07D 401/06 (2013.01); C07D 401/14 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9828980 A1 19980709; AU 6013998 A 19980731; CA 2276081 A1 19980709; EP 1003374 A1 20000531; EP 1003374 A4 20000531; JP 2002511054 A 20020409

DOCDB simple family (application)

US 9723888 W 19971222; AU 6013998 A 19971222; CA 2276081 A 19971222; EP 97954798 A 19971222; JP 53021498 A 19971222