Global Patent Index - EP 1003500 A1

EP 1003500 A1 2000-05-31 - INTRAMURAL DELIVERY OF NITRIC OXIDE ENHANCER FOR INHIBITING LESION FORMATION AFTER VASCULAR INJURY

Title (en)

INTRAMURAL DELIVERY OF NITRIC OXIDE ENHANCER FOR INHIBITING LESION FORMATION AFTER VASCULAR INJURY

Title (de)

INTRAMURALE VERABREICHUNG VON STICKSTOFF MONOXID ZUR HEMMUNG DER LÄSIONSBILDUNG NACH EINER GEFÄSSVERLETZUNG

Title (fr)

APPORT INTRAMURAL D'UN ACTIVATEUR DE MONOXYDE D'AZOTE AFIN D'INHIBER LA FORMATION DE LESIONS APRES BLESSURE VASCULAIRE

Publication

EP 1003500 A1 (EN)

Application

EP 97938163 A

Priority

  • US 9713905 W
  • US 69579296 A

Abstract (en)

[origin: WO9806389A1] Vessels suffering vascular injury from angioplasty are treated with L-arginine intramurally. The incidents associated with restenosis are substantially reduced providing for reduced incidents of restenosis as a result of the injury. An iontophoretic catheter can be used for local delivery of the L-arginine. In the catheter, one electrode (28) is located within the catheter body (11) while the other electrode (31) is located on the body surface or within the body of the patient. The catheter balloon (26) is then inflated with the drug entering the balloon interior (27) through lumen (23). Activation of the power supply (30) causes the drug to cross the balloon wall (26) and contact the surrounding vessel wall (15) and vascular tissue.

IPC 1-7 (main, further and additional classification)

A61K 31/195; A61M 25/10; A61M 29/02; A61N 1/30

IPC 8 full level (invention and additional information)

A61M 25/00 (2006.01); A23L 1/305 (2006.01); A61K 31/198 (2006.01); A61K 38/04 (2006.01); A61K 38/16 (2006.01); A61K 38/44 (2006.01); A61P 9/14 (2006.01); A61K 48/00 (2006.01)

CPC (invention and additional information)

A61K 31/198 (2013.01); A23L 33/175 (2016.08); A61K 48/00 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9806389 A1 19980219; DE 69637676 D1 20081023; EP 1003500 A1 20000531; EP 1003500 A4 20040623; JP 2000516612 A 20001212

INPADOC legal status


2009-09-30 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20090408

2007-01-17 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20061219

2004-06-23 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20040507

2004-06-23 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7A 61K 31/195 A

2004-06-23 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7A 61M 25/10 B

2004-06-23 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7A 61M 29/02 B

2004-06-23 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7A 61N 1/30 B

2000-05-31 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990310

2000-05-31 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE