EP 1003521 A1 20000531 - METHODS TO POTENTIATE INTRAVENOUS ESTRAMUSTINE PHOSPHATE
Title (en)
METHODS TO POTENTIATE INTRAVENOUS ESTRAMUSTINE PHOSPHATE
Title (de)
VERFAHREN ZUR POTENZIERUNG INTRAVENÖS ESTRAMUSTIN PHOSFAT
Title (fr)
PROCEDES DE POTENTIALISATION DE L'ESTRAMUSTINE PHOSPHATE INTRAVEINEUX
Publication
Application
Priority
- US 9904275 W 19990326
- US 7954298 P 19980327
Abstract (en)
[origin: WO9949869A1] Estramustine phosphate is an anti-mitotic chemotherapeutic drug with proven efficacy against cancer. The invention describes methods which potentiate the therapeutic benefit of intravenous estramustine phosphate. The invention provides for intravenous estramustine phosphate to be administrated at a high dosage exceeding 1300 mg as a single dose. Efficacious enhancement of estramustine phosphate pharmacokinetics is thereby achieved. Further provided, estramustine phosphate may be intravenously administered for use in combinational regimens with other chemotherapeutic agent. The therapeutic advantages achieved using the intravenous estramustine phosphate formulation are applicable to treatment of a variety of cancers including prostate cancer, breast cancer, lung cancer, colorectal cancer, pancreatic cancer, ovarian cancer, melanoma, and other cancers.
IPC 1-7
IPC 8 full level
A61K 9/127 (2006.01); A61K 9/08 (2006.01); A61K 31/337 (2006.01); A61K 31/437 (2006.01); A61K 31/4468 (2006.01); A61K 31/565 (2006.01); A61K 31/704 (2006.01); A61K 31/7042 (2006.01); A61P 35/00 (2006.01)
CPC (source: EP KR)
A61K 9/08 (2013.01 - EP); A61K 31/56 (2013.01 - KR); A61P 35/00 (2017.12 - EP)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9949869 A1 19991007; AU 3353399 A 19991018; AU 750010 B2 20020711; BR 9906425 A 20000711; CA 2295049 A1 19991007; CN 1273530 A 20001115; CN 1636598 A 20050713; EA 004647 B1 20040624; EA 199901081 A1 20001225; EP 1003521 A1 20000531; EP 1003521 A4 20030723; HU P0200547 A2 20020729; HU P0200547 A3 20030728; ID 24504 A 20000720; IL 133612 A0 20010430; JP 2001508810 A 20010703; KR 20010021656 A 20010315; NO 20002343 D0 20000504; NO 20002343 L 20000504; NZ 501987 A 20021025; PL 342969 A1 20010716; ZA 997821 B 20000801
DOCDB simple family (application)
US 9904275 W 19990326; AU 3353399 A 19990326; BR 9906425 A 19990326; CA 2295049 A 19990326; CN 200410086718 A 19990326; CN 99800823 A 19990326; EA 199901081 A 19990326; EP 99914884 A 19990326; HU P0200547 A 19990326; ID 20000105 A 19990326; IL 13361299 A 19990326; JP 54936999 A 19990326; KR 20007000214 A 20000110; NO 20002343 A 20000504; NZ 50198799 A 19990326; PL 34296999 A 19990326; ZA 997821 A 19991222