Global patent index - EP 1003527 A1

EP 1003527 A1 2000-05-31 - POLYNUCLEOTIDE COMPOSITIONS

Title (en)

POLYNUCLEOTIDE COMPOSITIONS

Title (de)

POLYNUKLEOTID ZUSAMMENSETZUNGEN

Title (fr)

COMPOSITIONS POLYNUCLEOTIDIQUES

Publication

EP 1003527 A1 (EN)

Application

EP 98938235 A

Priority

  • US 9816012 W
  • US 91296897 A
  • US 12494398 A

Abstract (en)

[origin: CA2298061A1] Compositions for stabilizing polynucleic acids and increasing the ability of polynucleic acids to cross cell membranes and act in the interior of a cell. In one aspect, the invention provides a polynucleotide complex between a polynucleotide and certain polyether block copolymers. The polynucleotide complex can further include a polycationic polymer, as well as suitable targeting molecules and surfactants. The invention also provides a polynucleotide complex between a polynucleotide and a block copolymer comprising a polyether block and a polycation block.

IPC 1-7 (main, further and additional classification)

A61K 31/735; C07H 21/04; C08F 283/00; C08F 293/00; C08L 1/00; C08L 71/02

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 31/70 (2006.01); A61K 31/7088 (2006.01); A61K 31/715 (2006.01); A61K 35/76 (2006.01); A61K 47/48 (2006.01); A61K 48/00 (2006.01); A61P 31/16 (2006.01); A61P 31/22 (2006.01); C07H 21/00 (2006.01); C07H 21/04 (2006.01); C08F 283/00 (2006.01); C08F 293/00 (2006.01); C08G 65/333 (2006.01); C08G 85/00 (2006.01); C08L 1/00 (2006.01); C08L 71/02 (2006.01); C12N 7/00 (2006.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

CA 2298061 A1 19990211; EP 1003527 A1 20000531; EP 1003527 A4 20030716; JP 2003526692 A 20030909

INPADOC legal status

2008-07-23 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20080201

2005-07-13 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20050527

2003-07-16 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20030602

2000-05-31 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000229

2000-05-31 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE