Global patent index - EP 1003743 A4

EP 1003743 A4 2001-04-11 - 3,3-DISUBSTITUTED PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

Title (en)

3,3-DISUBSTITUTED PIPERIDINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY

Title (de)

3,3-DISBSTITUIERTE PIPERIDINE WIE MODULATOREN VON CHEMOKINE-REZEPTOR AKTIVITÄT

Title (fr)

PIPERIDINES 3,3-DISUBSTITUEES UTILISEES COMME MODULATEURS DE L'ACTIVITE DE RECEPTEURS DE CHEMOKINES

Publication

EP 1003743 A4 (EN)

Application

EP 98905975 A

Priority

  • GB 9707490 A
  • US 9801101 W
  • US 3585497 P

Abstract (en)

[origin: WO9831364A1] The present invention is directed to 3,3-disubstituted piperidines of formula (I), (wherein X, Y, Z, Ar, R, m and n are defined herein) which are useful as modulators of chemokine receptor activity. In particular, these compounds are useful as modulators of the chemokine receptors CCR-1, CCR-2, CCR-2A, CCR-2B, CCR-3, CCR-4, CCR-5, CXCR-3, and/or CXCR-4.

IPC 1-7 (main, further and additional classification)

C07D 211/06; A61K 31/44; A61K 31/445; C07D 211/22; C07D 221/20; C07D 401/06; C07D 401/14

IPC 8 full level (invention and additional information)

C07D 221/20 (2006.01); A61K 31/438 (2006.01); A61K 31/445 (2006.01); A61K 31/4535 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61P 11/06 (2006.01); A61P 31/18 (2006.01); A61P 37/00 (2006.01); A61P 37/08 (2006.01); A61P 43/00 (2006.01); C07D 211/16 (2006.01); C07D 211/68 (2006.01); C07D 211/76 (2006.01); C07D 401/06 (2006.01); C07D 401/14 (2006.01); C07D 471/10 (2006.01)

CPC (invention and additional information)

C07D 401/06 (2013.01); A61K 31/438 (2013.01); A61K 31/4535 (2013.01); A61K 31/454 (2013.01); A61K 31/4545 (2013.01); C07D 211/16 (2013.01); C07D 211/76 (2013.01); C07D 401/14 (2013.01); C07D 471/10 (2013.01)

Citation (search report)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9831364 A1 19980723; AU 6133098 A 19980807; CA 2278309 A1 19980723; EP 1003743 A1 20000531; EP 1003743 A4 20010411; JP 2001508798 A 20010703

INPADOC legal status

2004-02-11 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20030801

2001-04-11 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20010228

2001-04-11 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2001-04-11 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- Free Format Text: 7C 07D 211/06 A, 7C 07D 211/22 B, 7C 07D 221/20 B, 7C 07D 401/06 B, 7C 07D 401/14 B, 7A 61K 31/44 B, 7A 61K 31/445 B

2000-05-31 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19990823

2000-05-31 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE