EP 1003846 A1 20000531 - PROTEASE INHIBITORS
Title (en)
PROTEASE INHIBITORS
Title (de)
PROTEASEINHIBITOREN
Title (fr)
INHIBITEURS DE PROTEASES
Publication
Application
Priority
- US 9803200 W 19980506
- US 4575897 P 19970506
Abstract (en)
[origin: WO9850533A1] The invention relates to 3-hydroxy- and 3-keto-cyclohetero-substituted leucine compounds that are inhibitors of cysteine proteases, particularly cathepsin K, and are useful in the treatment of diseases in which inhibition of bone loss is a factor. The 3-hydroxy- or 3-keto-moiety is bonded to a tetrahydrothiophene, tetrahydrothiopyran, tetrahydrofuran or tetrahydropyran ring.
IPC 1-7
C12N 9/99; C12N 9/50; A01N 43/02; A01N 43/06; A01N 43/08; A01N 43/16; A01N 43/18; C07D 307/00; C07D 307/48; C07D 309/00; C07D 319/06; C07D 321/00; C07D 333/02; C07D 333/12; C07D 333/22; C07D 335/00; C07D 335/02
IPC 8 full level
A61K 31/341 (2006.01); A61K 31/351 (2006.01); A61K 31/36 (2006.01); A61K 31/381 (2006.01); A61K 31/443 (2006.01); A61K 31/4709 (2006.01); A61P 1/02 (2006.01); A61P 19/00 (2006.01); A61P 19/02 (2006.01); A61P 19/10 (2006.01); C07D 307/22 (2006.01); C07D 307/32 (2006.01); C07D 307/33 (2006.01); C07D 307/83 (2006.01); C07D 307/86 (2006.01); C07D 309/30 (2006.01); C07D 333/36 (2006.01); C12N 9/99 (2006.01); C07D 405/12 (2006.01); C07D 407/12 (2006.01); C07D 409/12 (2006.01)
CPC (source: EP KR)
A61P 1/02 (2018.01 - EP); A61P 19/00 (2018.01 - EP); A61P 19/02 (2018.01 - EP); A61P 19/10 (2018.01 - EP); A61P 21/06 (2018.01 - EP); C07D 307/22 (2013.01 - EP); C07D 307/32 (2013.01 - EP); C07D 307/83 (2013.01 - EP); C07D 307/86 (2013.01 - EP); C07D 309/30 (2013.01 - EP); C07D 405/12 (2013.01 - EP); C07D 407/12 (2013.01 - EP); C07D 409/12 (2013.01 - EP); C12N 9/99 (2013.01 - KR)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9850533 A1 19981112; AR 013079 A1 20001213; AU 7562598 A 19981127; BR 9809306 A 20000704; CA 2288868 A1 19981112; CN 1255161 A 20000531; CO 4950618 A1 20000901; EP 1003846 A1 20000531; EP 1003846 A4 20021113; HU P0002247 A2 20010528; HU P0002247 A3 20030128; IL 132088 A0 20010319; JP 2001525804 A 20011211; KR 20010012256 A 20010215; NO 995434 D0 19991105; NO 995434 L 19991105; NZ 337889 A 20010928; PE 71599 A1 19990915; PL 336856 A1 20000717; TR 199902766 T2 20000221; UY 25143 A1 19981127; ZA 983762 B 19981106
DOCDB simple family (application)
US 9803200 W 19980506; AR P980102069 A 19980504; AU 7562598 A 19980506; BR 9809306 A 19980506; CA 2288868 A 19980506; CN 98804791 A 19980506; CO 98024945 A 19980506; EP 98923299 A 19980506; HU P0002247 A 19980506; IL 13208898 A 19980506; JP 54804998 A 19980506; KR 19997010207 A 19991105; NO 995434 A 19991105; NZ 33788998 A 19980506; PE 00033698 A 19980505; PL 33685698 A 19980506; TR 9902766 T 19980506; UY 25143 A 19980817; ZA 983762 A 19980505