Global Patent Index - EP 1003881 A2

EP 1003881 A2 2000-05-31 - TRANSFORMED YEAST STRAINS AND THEIR USE FOR THE PRODUCTION OF MONOTERMINAL AND DITERMINAL ALIPHATIC CARBOXYLATES

Title (en)

TRANSFORMED YEAST STRAINS AND THEIR USE FOR THE PRODUCTION OF MONOTERMINAL AND DITERMINAL ALIPHATIC CARBOXYLATES

Title (de)

TRANSFORMIERTE HEFESTÄMME UND IHRE VERWENDUNG ZUR HERSTELLUNG VON MONO- UND DI-TERMINALEN ALIPHATISCHEN CARBOXYLATEN

Title (fr)

SOUCHES DE LEVURE TRANSFORMEES ET LEUR UTILISATION DANS LA PRODUCTION DE CARBOXYLATES ALIPHATIQUES A TERMINAISON UNIQUE ET DOUBLE

Publication

EP 1003881 A2 (EN)

Application

EP 98935806 A

Priority

  • US 9814935 W
  • US 5321597 P

Abstract (en)

[origin: WO9904014A2] The present invention comprises a bioprocess for converting aliphatic compounds, of the form CH3(CH2)nCH3 where n = 4 to 20, to monoterminal and diterminal carboxylates using genetically-engineered organisms. This invention relates to a process for expressing alkane hydroxylating activity in genetically-engineered yeasts Pichia pastoris and Candida maltosa. In addition, the present invention describes a process to produce genetically transformed Candida maltosa strains that have enhanced cytochrome P450 activity and/or gene disruptions in the beta -oxidation pathway.

IPC 1-7 (main, further and additional classification)

C12N 15/53; C12P 7/44; C12P 7/40

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); C12N 1/15 (2006.01); C12N 9/02 (2006.01); C12N 15/53 (2006.01); C12P 7/40 (2006.01); C12P 7/44 (2006.01); C12R 1/84 (2006.01)

CPC (invention and additional information)

C12N 9/0042 (2013.01); C12N 9/0077 (2013.01); C12P 7/40 (2013.01); C12P 7/44 (2013.01); C12R 1/72 (2013.01); C12R 1/84 (2013.01)

Designated contracting state (EPC)

DE DK ES FR GB IE IT NL SE

EPO simple patent family

WO 9904014 A2 19990128; WO 9904014 A3 19990520; AU 8498298 A 19990210; CA 2293737 A1 19990128; EP 1003881 A2 20000531; IL 133931 D0 20010430; JP 2001510048 A 20010731

INPADOC legal status


2005-04-27 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20041015

2004-07-14 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: E.I. DU PONT DE NEMOURS AND COMPANY

2001-09-05 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20010720

2000-05-31 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000114

2000-05-31 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): DE DK ES FR GB IE IT NL SE