EP 1003909 A1 20000531 - REPRODUCTIVE AND GENETIC SCREENING SAMPLES OF MUTAGENISED ANIMALS
Title (en)
REPRODUCTIVE AND GENETIC SCREENING SAMPLES OF MUTAGENISED ANIMALS
Title (de)
REPRODUKTIONS- UND GENETISCHES UNTERSUCHUNGSMATERIAL VON MUTAGENISIERTEN TIEREN
Title (fr)
ECHANTILLONS DE CRIBLAGE DE REPRODUCTION ET GENETIQUE D'ANIMAUX MUTAGENISES
Publication
Application
Priority
- GB 9801945 W 19980702
- GB 9714023 A 19970702
Abstract (en)
[origin: WO9901577A1] The invention provides a collection of paired samples from a plurality of mutagenised animals, wherein each paired sample comprises: a first sample comprising genetic screening material from a parent animal; and a second sample comprising reproductive material from that same parent animal. The reproductive material is preferably gametes. It also provides methods for producing and screening the collection, for instance to identify a gamete sample in such a collection known to carry a mutation in a gene of interest. This gamete sample can be used to generate an animal carrying that same mutation. The mutant animal is useful for investigating the function of the gene, and might also be a useful animal model for studying human disease. In effect, therefore, the mutations in a population of mutagenised animals are immortalised and animals carrying particular mutations of interest can be produced easily without the need to maintain a living animal population.
IPC 1-7
IPC 8 full level
A01K 67/027 (2006.01); A01N 1/00 (2006.01); C12N 5/06 (2006.01); C12N 5/07 (2010.01); C12N 5/071 (2010.01); C12Q 1/68 (2006.01)
CPC (source: EP)
A01K 67/027 (2013.01); C12Q 1/68 (2013.01)
Citation (search report)
See references of WO 9901577A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9901577 A1 19990114; AU 742368 B2 20020103; AU 8228598 A 19990125; CA 2296019 A1 19990114; EP 1003909 A1 20000531; GB 9714023 D0 19970910; IL 133810 A0 20010430; JP 2002508671 A 20020319
DOCDB simple family (application)
GB 9801945 W 19980702; AU 8228598 A 19980702; CA 2296019 A 19980702; EP 98932346 A 19980702; GB 9714023 A 19970702; IL 13381098 A 19980702; JP 50666699 A 19980702