EP 1007003 A1 20000614 - CATIONIC AMPHIPHILE COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES
Title (en)
CATIONIC AMPHIPHILE COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES
Title (de)
KATIONISCHE AMPHIPHILE ZUSAMMENSETZUNGEN ZUR INTRAZELLULÄREN ZUFUHR VON THERAPEUTISCH WIRKSAMEN MOLEKÜLEN
Title (fr)
COMPOSITIONS AMPHIPHILES CATIONIQUES DESTINEES A UN APPORT INTRACELLULAIRE DE MOLECULES THERAPEUTIQUES
Publication
Application
Priority
US 9709748 W 19970610
Abstract (en)
[origin: WO9813026A1] Novel cationic amphiphiles are provided that facilitate transport of biologically active (therapeutic) molecules into cells. By this invention, such cationic amphiphile is used in a state in which it is capable of accepting additional protons, i.e., it is not fully protonated. For purposes of this invention, cationic amphiphiles may be considered to encompass four general categories: (A) T-shaped/steroid-based amphiphiles; (B) T-shaped/non steroid-based amphiphils; (C) non T-shaped/steroid based amphiphiles and (D) non T-shaped/non steroid-based amphiphiles.
IPC 1-7
IPC 8 full level
A61K 9/127 (2006.01); A61K 31/7088 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); C12N 15/18 (2006.01); C12N 15/88 (2006.01)
CPC (source: EP)
A61K 9/1272 (2013.01); C12N 15/88 (2013.01)
Citation (search report)
See references of WO 9813026A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9813026 A1 19980402; CA 2268945 A1 19980402; EP 1007003 A1 20000614; JP 2001500897 A 20010123
DOCDB simple family (application)
US 9709748 W 19970610; CA 2268945 A 19970610; EP 97927989 A 19970610; JP 51560398 A 19970610