Global patent index - EP 1007003 A1

EP 1007003 A1 2000-06-14 - CATIONIC AMPHIPHILE COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES

Title (en)

CATIONIC AMPHIPHILE COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC MOLECULES

Title (de)

KATIONISCHE AMPHIPHILE ZUSAMMENSETZUNGEN ZUR INTRAZELLULÄREN ZUFUHR VON THERAPEUTISCH WIRKSAMEN MOLEKÜLEN

Title (fr)

COMPOSITIONS AMPHIPHILES CATIONIQUES DESTINEES A UN APPORT INTRACELLULAIRE DE MOLECULES THERAPEUTIQUES

Publication

EP 1007003 A1 (EN)

Application

EP 97927989 A

Priority

US 9709748 W

Abstract (en)

[origin: WO9813026A1] Novel cationic amphiphiles are provided that facilitate transport of biologically active (therapeutic) molecules into cells. By this invention, such cationic amphiphile is used in a state in which it is capable of accepting additional protons, i.e., it is not fully protonated. For purposes of this invention, cationic amphiphiles may be considered to encompass four general categories: (A) T-shaped/steroid-based amphiphiles; (B) T-shaped/non steroid-based amphiphils; (C) non T-shaped/steroid based amphiphiles and (D) non T-shaped/non steroid-based amphiphiles.

IPC 1-7 (main, further and additional classification)

A61K 9/127; C07H 21/00; C12N 15/88

IPC 8 full level (invention and additional information)

A61K 9/127 (2006.01); A61K 31/7088 (2006.01); A61K 45/00 (2006.01); A61K 48/00 (2006.01); C12N 15/18 (2006.01); C12N 15/88 (2006.01)

CPC (invention and additional information)

C12N 15/88 (2013.01); A61K 9/1272 (2013.01)

Citation (search report)

See references of WO 9813026A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9813026 A1 19980402; AU 3231597 A 19980417; CA 2268945 A1 19980402; EP 1007003 A1 20000614; JP 2001500897 A 20010123

INPADOC legal status

2004-07-14 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20040103

2000-06-14 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19981230

2000-06-14 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE