Global Patent Index - EP 1007026 A1

EP 1007026 A1 20000614 - INTEGRIN ANTAGONISTS

Title (en)

INTEGRIN ANTAGONISTS

Title (de)

INTEGRIN-ANTAGONISTEN

Title (fr)

ANTAGONISTES D'INTEGRINE

Publication

EP 1007026 A1 20000614 (EN)

Application

EP 98903466 A 19980113

Priority

  • GB 9702788 A 19970211
  • GB 9725996 A 19971209
  • US 9800617 W 19980113
  • US 3561497 P 19970117
  • US 6259497 P 19971020

Abstract (en)

[origin: WO9831359A1] This invention relates to certain novel compounds and derivatives thereof, their synthesis, and their use as vitronectin receptor antagonists. The vitronectin receptor antagonist compounds of the present invention are alpha v beta 3 antagonists, alpha v beta 5 antagonists or dual alpha v beta 3/ alpha v beta 5 antagonists useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, viral disease, and tumor growth.

IPC 1-7

A61K 31/18; A61K 31/19; A61K 31/44; A61K 31/47; A61K 31/195; A61K 31/405; A61K 31/415; A61K 31/425; A61K 31/435; C07C 63/00; C07C 307/06; C07C 307/08; C07C 307/10; C07D 213/89; C07D 217/08; C07D 233/44; C07D 233/88; C07D 239/08; C07D 239/42; C07D 209/40

IPC 8 full level

C07D 235/16 (2006.01); A61K 31/198 (2006.01); A61K 31/4184 (2006.01); A61K 31/4375 (2006.01); A61K 31/44 (2006.01); A61K 31/66 (2006.01); A61K 45/06 (2006.01); A61P 9/10 (2006.01); A61P 19/10 (2006.01); A61P 27/02 (2006.01); A61P 29/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 213/73 (2006.01); C07D 471/04 (2006.01)

CPC (source: EP)

A61K 31/66 (2013.01); A61P 9/10 (2017.12); A61P 19/10 (2017.12); A61P 27/02 (2017.12); A61P 29/00 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07D 471/04 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

DOCDB simple family (publication)

WO 9831359 A1 19980723; AU 6023198 A 19980807; AU 729869 B2 20010215; CA 2277273 A1 19980723; CA 2277273 C 20080325; EP 1007026 A1 20000614; EP 1007026 A4 20020807; JP 2001509176 A 20010710

DOCDB simple family (application)

US 9800617 W 19980113; AU 6023198 A 19980113; CA 2277273 A 19980113; EP 98903466 A 19980113; JP 53447398 A 19980113