Global patent index - EP 1007026 A1

EP 1007026 A1 2000-06-14 - INTEGRIN ANTAGONISTS

Title (en)

INTEGRIN ANTAGONISTS

Title (de)

INTEGRIN-ANTAGONISTEN

Title (fr)

ANTAGONISTES D'INTEGRINE

Publication

EP 1007026 A1 (EN)

Application

EP 98903466 A

Priority

  • GB 9702788 A
  • GB 9725996 A
  • US 9800617 W
  • US 3561497 P
  • US 6259497 P

Abstract (en)

[origin: WO9831359A1] This invention relates to certain novel compounds and derivatives thereof, their synthesis, and their use as vitronectin receptor antagonists. The vitronectin receptor antagonist compounds of the present invention are alpha v beta 3 antagonists, alpha v beta 5 antagonists or dual alpha v beta 3/ alpha v beta 5 antagonists useful for inhibiting bone resorption, treating and preventing osteoporosis, and inhibiting restenosis, diabetic retinopathy, macular degeneration, angiogenesis, atherosclerosis, inflammation, viral disease, and tumor growth.

IPC 1-7 (main, further and additional classification)

A61K 31/18; A61K 31/19; A61K 31/195; A61K 31/405; A61K 31/415; A61K 31/425; A61K 31/435; A61K 31/44; A61K 31/47; C07C 63/00; C07C 307/06; C07C 307/08; C07C 307/10; C07D 209/40; C07D 213/89; C07D 217/08; C07D 233/44; C07D 233/88; C07D 239/08; C07D 239/42

IPC 8 full level (invention and additional information)

C07D 235/16 (2006.01); A61K 31/198 (2006.01); A61K 31/4184 (2006.01); A61K 31/4375 (2006.01); A61K 31/44 (2006.01); A61K 31/66 (2006.01); A61K 45/06 (2006.01); A61P 9/10 (2006.01); A61P 19/10 (2006.01); A61P 27/02 (2006.01); A61P 29/00 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 213/73 (2006.01); C07D 471/04 (2006.01)

CPC (invention and additional information)

C07D 471/04 (2013.01); A61K 31/66 (2013.01)

Combination set (CPC)

  1. A61K 31/66 + A61K 31/445
  2. A61K 31/66 + A61K 2300/00

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9831359 A1 19980723; AU 6023198 A 19980807; AU 729869 B2 20010215; CA 2277273 A1 19980723; CA 2277273 C 20080325; EP 1007026 A1 20000614; EP 1007026 A4 20020807; JP 2001509176 A 20010710

INPADOC legal status

2004-09-15 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20040306

2003-10-08 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20030826

2002-08-07 [A4] SUPPLEMENTARY SEARCH REPORT

- Ref Legal Event Code: A4

- Effective date: 20020620

2002-08-07 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2002-05-02 [RIC1] CLASSIFICATION (CORRECTION)

- Ref Legal Event Code: RIC1

- Free Format Text: 7C 07D 471/04 A, 7A 61K 31/445 B

2000-06-14 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 19990817

2000-06-14 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU NL PT SE