Global Patent Index - EP 1007038 A2

EP 1007038 A2 20000614 - ANTI-INFLAMMATORY AGENT

Title (en)

ANTI-INFLAMMATORY AGENT

Title (de)

ENTZÜNDUNGSHEMMENDES MITTEL

Title (fr)

AGENT ANTIINFLAMMATOIRE

Publication

EP 1007038 A2 20000614 (EN)

Application

EP 98938913 A 19980820

Priority

  • JP 9803692 W 19980820
  • JP 22530297 A 19970821

Abstract (en)

[origin: WO9909965A2] An anti-inflammatory agent which affects by way of a TNF- alpha inhibitory action and comprises a compound of formula (I) wherein R represents a hydrocarbon group that may be substituted or a heterocyclic group that may be substituted; Y represents a group of the formula -CO-, -CH(OH)-, or -NR<3>- where R<3> represents an alkyl group that may be substituted; m is 0 or 1; n is 0, 1 or 2; X represents CH or N; A represents a chemical bond or a bivalent aliphatic hydrocarbon group having 1 to 7 carbon atoms; Q represents oxygen or sulfur; R<1> represents hydrogen or an alkyl group; ring E may have further 1 to 4 substituents, which may form a ring in combination with R<1>; L and M respectively represent hydrogen or may be combined with each other to form a chemical bond or a salt thereof.

[origin: WO9909965A2] An anti-inflammatory agent which affects by way of a TNF- alpha inhibitory action and comprises a compound of formula (I) wherein R represents a hydrocarbon group that may be substituted or a heterocyclic group that may be substituted; Y represents a group of the formula -CO-, -CH(OH)-, or -NR<3>- where R<3> represents an alkyl group that may be substituted; m is 0 or 1; n is 0, 1 or 2; X represents CH or N; A represents a chemical bond or a bivalent aliphatic hydrocarbon group having 1 to 7 carbon atoms; Q represents oxygen or sulfur; R<1> represents hydrogen or an alkyl group; ring E may have further 1 to 4 substituents, which may form a ring in combination with R<1>; L and M respectively represent hydrogen or may be combined with each other to form a chemical bond or a salt thereof.

IPC 1-7

A61K 31/42; A61K 31/44

IPC 8 full level

A61K 31/422 (2006.01); A61K 31/427 (2006.01); A61K 31/4439 (2006.01)

CPC (source: EP)

A61K 31/422 (2013.01); A61K 31/427 (2013.01); A61K 31/4439 (2013.01)

Citation (search report)

See references of WO 9909965A2

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

WO 9909965 A2 19990304; WO 9909965 A3 19990520; AU 8747998 A 19990316; CA 2300813 A1 19990304; EP 1007038 A2 20000614

DOCDB simple family (application)

JP 9803692 W 19980820; AU 8747998 A 19980820; CA 2300813 A 19980820; EP 98938913 A 19980820