Global Patent Index - EP 1007038 A2

EP 1007038 A2 2000-06-14 - ANTI-INFLAMMATORY AGENT

Title (en)

ANTI-INFLAMMATORY AGENT

Title (de)

ENTZÜNDUNGSHEMMENDES MITTEL

Title (fr)

AGENT ANTIINFLAMMATOIRE

Publication

EP 1007038 A2 (EN)

Application

EP 98938913 A

Priority

  • JP 9803692 W
  • JP 22530297 A

Abstract (en)

[origin: WO9909965A2] An anti-inflammatory agent which affects by way of a TNF- alpha inhibitory action and comprises a compound of formula (I) wherein R represents a hydrocarbon group that may be substituted or a heterocyclic group that may be substituted; Y represents a group of the formula -CO-, -CH(OH)-, or -NR<3>- where R<3> represents an alkyl group that may be substituted; m is 0 or 1; n is 0, 1 or 2; X represents CH or N; A represents a chemical bond or a bivalent aliphatic hydrocarbon group having 1 to 7 carbon atoms; Q represents oxygen or sulfur; R<1> represents hydrogen or an alkyl group; ring E may have further 1 to 4 substituents, which may form a ring in combination with R<1>; L and M respectively represent hydrogen or may be combined with each other to form a chemical bond or a salt thereof.

[origin: WO9909965A2] An anti-inflammatory agent which affects by way of a TNF- alpha inhibitory action and comprises a compound of formula (I) wherein R represents a hydrocarbon group that may be substituted or a heterocyclic group that may be substituted; Y represents a group of the formula -CO-, -CH(OH)-, or -NR<3>- where R<3> represents an alkyl group that may be substituted; m is 0 or 1; n is 0, 1 or 2; X represents CH or N; A represents a chemical bond or a bivalent aliphatic hydrocarbon group having 1 to 7 carbon atoms; Q represents oxygen or sulfur; R<1> represents hydrogen or an alkyl group; ring E may have further 1 to 4 substituents, which may form a ring in combination with R<1>; L and M respectively represent hydrogen or may be combined with each other to form a chemical bond or a salt thereof.

IPC 1-7 (main, further and additional classification)

A61K 31/42; A61K 31/44

IPC 8 full level (invention and additional information)

A61K 31/422 (2006.01); A61K 31/427 (2006.01); A61K 31/4439 (2006.01)

CPC (invention and additional information)

A61K 31/4439 (2013.01); A61K 31/422 (2013.01); A61K 31/427 (2013.01)

Citation (search report)

See references of WO 9909965A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9909965 A2 19990304; WO 9909965 A3 19990520; AU 8747998 A 19990316; CA 2300813 A1 19990304; EP 1007038 A2 20000614

INPADOC legal status


2004-06-16 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20031215

2002-05-29 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020411

2000-06-14 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991122

2000-06-14 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE