Global Patent Index - EP 1007073 A1

EP 1007073 A1 2000-06-14 - METHODS OF MODIFYING FEEDING BEHAVIOR, COMPOUNDS USEFUL IN SUCH METHODS, AND DNA ENCODING A HYPOTHALAMIC ATYPICAL NEUROPEPTIDE Y/PEPTIDE YY RECEPTOR (Y5)

Title (en)

METHODS OF MODIFYING FEEDING BEHAVIOR, COMPOUNDS USEFUL IN SUCH METHODS, AND DNA ENCODING A HYPOTHALAMIC ATYPICAL NEUROPEPTIDE Y/PEPTIDE YY RECEPTOR (Y5)

Title (de)

VERFAHREN ZUR ÄNDERUNG DER ESSGEWOHNHEITEN, FÜR DIESE VERFAHREN GEEIGNETE VERBINDUNGEN, SOWIE EINE FÜR EINEN HYPOTHALAMISCHES ATYPISCHES NEUROPEPTID Y/ PEPTIDE YY REZEPTOR KODIERENDE DNA

Title (fr)

PROCEDES DE MODIFICATION DU COMPORTEMENT ALIMENTAIRE, COMPOSES UTILES DANS LESDITS PROCEDES, ET ADN CODANT UN RECEPTEUR Y5 ATYPIQUE HYPOTHALAMIQUE DE NEUROPEPTIDE Y/PEPTIDE YY

Publication

EP 1007073 A1 (EN)

Application

EP 97928786 A

Priority

  • US 9709504 W
  • US 66865096 A
  • US 80360097 A

Abstract (en)

[origin: WO9746250A1] The invention provides methods of modifying feeding behavior, including increasing or decreasing food consumption, e.g., in connection with treating obesity, bulimia or anorexia. These methods involve administration of compounds that are selective agonists or antagonists for the Y5 receptor. One such compound has structure (I). In addition, this invention provides an isolated nucleic acid molecule encoding a Y5 receptor, an isolated Y5 receptor protein, vectors comprising an isolated nucleic acid molecule encoding a Y5 receptor, cells comprising such vectors, antibodies directed to the Y5 receptor, nucleic acid probes useful for detecting nucleic acid encoding Y5 receptors, antisense aligonucleotides complementary to any unique sequences of a nucleic acid molecule which encodes a Y5 receptor, and nonhuman transgenic animals which express DNA encoding a normal or a mutant Y5 receptor.

IPC 1-7 (main, further and additional classification)

A61K 38/02; A61K 39/395; A61K 48/00; C07H 21/02; C07H 21/04; C07K 14/00; C07K 14/435; C07K 14/705; C07K 16/00; C12N 15/00; C12N 15/12

IPC 8 full level (invention and additional information)

C07K 14/705 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

C07K 14/70571 (2013.01); A01K 2217/05 (2013.01); A61K 38/00 (2013.01)

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9746250 A1 19971211; AU 3295297 A 19980105; EP 1007073 A1 20000614; EP 1007073 A4 20020327

INPADOC legal status


2006-03-08 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20050830

2003-11-05 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030917

2002-03-27 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20020213

2002-03-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-06-14 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990104

2000-06-14 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE