Global Patent Index - EP 1007083 A1

EP 1007083 A1 2000-06-14 - STABILISATION OF INTERFERONS IN AQUEOUS SOLUTION FOR MANUFACTURE OF SUBLINGUALLY ADMINISTERED TABLETS

Title (en)

STABILISATION OF INTERFERONS IN AQUEOUS SOLUTION FOR MANUFACTURE OF SUBLINGUALLY ADMINISTERED TABLETS

Title (de)

STABILISIERUNG VON WÄSSRIGEN INTERFERON-LÖSUNGEN ZUR HERSTELLUNG VON SUBLINGUALEN TABLETTEN

Title (fr)

STABILISATION D'INTERFERONS DANS UNE SOLUTION AQUEUSE EN VUE DE LA FABRICATION DE PASTILLES QUE L'ON ADMINISTRE PAR VOIE SUBLINGUALE

Publication

EP 1007083 A1 (EN)

Application

EP 97919595 A

Priority

IB 9700530 W

Abstract (en)

[origin: WO9851328A1] Natural and recombinant interferons are stabilised with bidistilled water, lactose, albumin, sodium mono-and dihydrophosphates, (C5H10O5)n, such arabic gum. The material obtained is sprayed on to an excipient comprising of 20 % arabic gum, 30 % lactose and 50 % starch for manufacturing tablets of 100 mg each containing 200 I.U. of human alfa-interferon. The final solution is sprayed on to an excipient comprising of 20 % arabic gum, 30 % lactose and 50 % starch for manufacturing tablets of 100 mg each containing 200 I.U. of human alfa-interferon. The tablets are sublingually administered to the patient for treatment of viral infections sensitive to interferon, such as AIDS.

IPC 1-7 (main, further and additional classification)

A61K 38/21; A61K 9/20; A61K 47/36

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 9/00 (2006.01); A61K 9/20 (2006.01); A61K 38/21 (2006.01); A61K 47/36 (2006.01); A61P 31/12 (2006.01); A61P 37/02 (2006.01); C07K 14/47 (2006.01); C07K 14/555 (2006.01); A61K 9/16 (2006.01); A61K 47/42 (2006.01)

CPC (invention and additional information)

A61K 9/0056 (2013.01); A61K 9/006 (2013.01); A61K 38/21 (2013.01); A61K 47/36 (2013.01); A61K 9/1623 (2013.01); A61K 9/1652 (2013.01); A61K 47/42 (2013.01)

Citation (search report)

See references of WO 9851328A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9851328 A1 19981119; AU 2401097 A 19981208; AU 730020 B2 20010222; EP 1007083 A1 20000614; JP 2001526662 A 20011218

INPADOC legal status


2002-09-04 [R18D] EP-APPLICATION DEEMED TO BE WITHDRAWN: (CORRECTION)

- Effective date: 20020302

2000-10-18 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20000901

2000-08-16 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: FERONPATENT LIMITED

2000-06-14 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991007

2000-06-14 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE