Global Patent Index - EP 1007540 A4

EP 1007540 A4 2003-06-18 - DNA MOLECULES ENCODING HUMAN NUCLEAR RECEPTOR PROTEINS

Title (en)

DNA MOLECULES ENCODING HUMAN NUCLEAR RECEPTOR PROTEINS

Title (de)

DNS MOLEKÜLE DIE PROTEINE DES MENSCHLICHEN KERNREZEPTORS KODIEREN

Title (fr)

MOLECULES D'ADN CODANT POUR DES PROTEINES RECEPTRICES NUCLEAIRES

Publication

EP 1007540 A4 (EN)

Application

EP 98943441 A

Priority

  • US 9817826 W
  • US 5709097 P
  • US 6290297 P
  • US 7863398 P

Abstract (en)

[origin: WO9910367A1] The present invention discloses the isolation and characterization of cDNA molecules encoding two human nuclear receptor proteins, designated nNR1, nNR2 and/or nNR2-1. Also within the scope of the disclosure are recombinant vectors, recombinant host cells, methods of screening for modulators of nNR1, nNR2 and/or nNR2-1 activity, and production of antibodies against nNR1, nNR2 and/or nNR2-1, or epitopes thereof.

IPC 1-7 (main, further and additional classification)

C07H 21/04; C07K 14/705; C12N 15/09; C12N 15/63; C12Q 1/68

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); C07K 14/705 (2006.01); C12N 1/15 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12P 21/02 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C07K 14/70567 (2013.01)

Citation (search report)

  • [X] ENMARK E ET AL: "ORPHAN NUCLEAR RECEPTORS - THE FIRST EIGHT YEARS", MOLECULAR ENDOCRINOLOGY, BALTIMORE, MD, US, vol. 10, no. 11, 1 November 1996 (1996-11-01), pages 1293 - 1307, XP000645166, ISSN: 0888-8809
  • [X] DATABASE EMBL [online] 27 January 1996 (1996-01-27), "yw88d02.r1 Homo sapiens cDNA clone 259299 5' similar to PIR:JC2390 JC2390 nuclear receptor Rev-ErbA beta - rat [1]", XP002239020, retrieved from EBI Database accession no. N41813
  • [X] DATABASE EMBL [online] 8 April 1995 (1995-04-08), "yd21f09.r1 Homo sapiens cDNA clone 67817 5' similar to SP:ROR1_HUMAN P35397 NUCLEAR RECEPTOR", XP002239021, retrieved from EBI Database accession no. T79024
  • [X] DATABASE EMBL [online] 29 May 1995 (1995-05-29), "yg96e07.r1 Homo sapiens cDNA clone 41139 5' similar to SP:RNR1_RAT Q07917 REGENERATING LIVER NUCLEAR RECEPTOR 1", XP002239022, retrieved from EBI Database accession no. R59032
  • [XD] DATABASE EMBL [online] 1 December 1995 (1995-12-01), "ys81d07.r1 Homo sapiens cDNA clone 221197 5' similar to gb:X51417_cds1 STEROID HORMONE RECEPTOR ERR2 (HUMAN)", XP002239023, retrieved from EBI Database accession no. H91890
  • [X] DATABASE EMBL [online] 16 November 1995 (1995-11-16), "ys69h11.r1 Homo sapiens cDNA clone 220101 5' similar to gb:X51417_cds1 STEROID HORMONE RECEPTOR ERR2 (HUMAN)", XP002239024, retrieved from EBI Database accession no. H82542
  • [X] DATABASE EMBL [online] 16 November 1995 (1995-11-16), "ys69h11.s1 Homo sapiens cDNA clone 220101 3' similar to gb:X51417_cds1 STEROID HORMONE RECEPTOR ERR2 (HUMAN)", XP002239025, retrieved from EBI Database accession no. H82543
  • [X] DATABASE EMBL [online] 1 December 1995 (1995-12-01), "ys81d07.s1 Homo sapiens cDNA clone 221197 3' similar to gb:X51417_cds1 STEROID HORMONE RECEPTOR ERR2 (HUMAN)", XP002239026, retrieved from EBI Database accession no. H91842
  • See also references of WO 9910367A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9910367 A1 19990304; CA 2301554 A1 19990304; EP 1007540 A1 20000614; EP 1007540 A4 20030618; JP 2001513984 A 20010911

INPADOC legal status


2004-02-25 [18W] APPLICATION WITHDRAWN

- Effective date: 20031208

2004-01-28 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20031211

2003-06-18 [A4] DESPATCH OF SUPPLEMENTARY SEARCH REPORT

- Effective date: 20030508

2000-06-14 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000327

2000-06-14 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE