EP 1007635 A1 20000614 - AGENT FOR DEHYDRATING CORNEAS IN ORGAN CULTURE
Title (en)
AGENT FOR DEHYDRATING CORNEAS IN ORGAN CULTURE
Title (de)
MITTEL ZUR ENTQUELLUNG VON HORNHÄUTEN IN DER ORGANKULTUR
Title (fr)
AGENT DE DESHYDRATATION DE CORNEES EN CULTURE D'ORGANES
Publication
Application
Priority
- DE 19702210 A 19970123
- EP 9800324 W 19980122
Abstract (en)
[origin: DE19702210A1] An agent for dehydrating corneas, in particular eye corneas for organ culture, contains the culture medium and as dehydrating substance hydroxyethylstarch with a mean molecular weight MW from 70,000 to 200,000, an MS substitution degree from 0.15 to 0.5, a DS substitution degree from 0.15 to 0.5 and a C2-C6 substitution ratio at the anhydroglucose units >/= 8. The dehydrating substance is preferably hydroxyethylstarch with a mean molecular weight MW 130,000 +/- 20,000, an MS substitution degree from 0.38 to 0.45, a DS substitution degree from 0.32 to 0.40 and a C2-C6 substitution ratio at the anhydroglucose units from 8 to 20. The hydroxyethylstarch is used in a concentration from 1 to 20 (weight/vol.) %, preferably from 2 to 15 (weight/vol.) %, and in particular of 7.5 % (weight/vol.). Also disclosed is the use of this hydroxyethylstarch as a dehydrating substance for the organ culture of corneas, in particular eye corneas, and the use of this hydroxyethylstarch for preparing a dehydrating agent for corneas, in particular eye corneas for organ culture.
IPC 1-7
IPC 8 full level
A01N 1/02 (2006.01); A61L 27/00 (2006.01); C08B 31/02 (2006.01); C12N 5/06 (2006.01); C12N 5/07 (2010.01); C12N 5/071 (2010.01); C12N 5/08 (2006.01)
CPC (source: EP)
A01N 1/02 (2013.01); A01N 1/0205 (2013.01)
Citation (search report)
See references of WO 9832839A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
DE 19702210 A1 19980806; DE 19702210 C2 19990114; EP 1007635 A1 20000614; JP 2001510996 A 20010807; WO 9832839 A1 19980730
DOCDB simple family (application)
DE 19702210 A 19970123; EP 9800324 W 19980122; EP 98904113 A 19980122; JP 53157298 A 19980122