Global Patent Index - EP 1007652 A1

EP 1007652 A1 2000-06-14 - TRANSGENIC ANIMALS WITH KNOCKED-IN VEC RECEPTOR GENES AND USES THEREOF

Title (en)

TRANSGENIC ANIMALS WITH KNOCKED-IN VEC RECEPTOR GENES AND USES THEREOF

Title (de)

TRANSGENE TIERE MIT KNOCKED-IN VEC REZEPTORGENEN UND DEREN VERWENDUNGEN

Title (fr)

ANIMAUX TRANSGENIQUES DONT LES GENES DES RECEPTEURS VEC SONT RENTRES DE FORCE, ET UTILISATIONS CORRESPONDANTES

Publication

EP 1007652 A1 (EN)

Application

EP 98949716 A

Priority

  • US 9820717 W
  • US 94338197 A

Abstract (en)

[origin: WO9918191A1] The present invention provides a non-human transgenic animal whose cells express a foreign DNA sequence that encodes a functional vascular endothelial cell receptor domain, but do not express a substantially homologous native DNA sequence. This invention also provides methods of using these transgenic animals for identifying therapeutic and other reagents that affect angiogenesis. Additionally provided are methods of using transgenic animals whose cells contain any donor genes as models for testing various reagents.

IPC 1-7 (main, further and additional classification)

C12N 15/00; A01K 67/00; G01N 33/00

IPC 8 full level (invention and additional information)

A01K 67/027 (2006.01); A61K 45/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 14/71 (2006.01); C12N 15/09 (2006.01); C12N 15/85 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01)

CPC (invention and additional information)

C12N 15/8509 (2013.01); A01K 67/0271 (2013.01); A01K 67/0275 (2013.01); A01K 67/0276 (2013.01); C07K 14/71 (2013.01); A01K 2217/05 (2013.01); A01K 2217/072 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/03 (2013.01); C07K 2319/00 (2013.01)

Citation (search report)

See references of WO 9918191A1

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB IE IT LI NL SE

EPO simple patent family

WO 9918191 A1 19990415; AU 9598598 A 19990427; CA 2305045 A1 19990415; EP 1007652 A1 20000614; JP 2001519145 A 20011023

INPADOC legal status


2002-10-23 [18W] WITHDRAWN

- Ref Legal Event Code: 18W

- Date of withdrawal: 20020830

2000-06-14 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000329

2000-06-14 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE DK ES FR GB IE IT LI NL SE