EP 1007652 A1 20000614 - TRANSGENIC ANIMALS WITH KNOCKED-IN VEC RECEPTOR GENES AND USES THEREOF
Title (en)
TRANSGENIC ANIMALS WITH KNOCKED-IN VEC RECEPTOR GENES AND USES THEREOF
Title (de)
TRANSGENE TIERE MIT KNOCKED-IN VEC REZEPTORGENEN UND DEREN VERWENDUNGEN
Title (fr)
ANIMAUX TRANSGENIQUES DONT LES GENES DES RECEPTEURS VEC SONT RENTRES DE FORCE, ET UTILISATIONS CORRESPONDANTES
Publication
Application
Priority
- US 9820717 W 19981002
- US 94338197 A 19971002
Abstract (en)
[origin: WO9918191A1] The present invention provides a non-human transgenic animal whose cells express a foreign DNA sequence that encodes a functional vascular endothelial cell receptor domain, but do not express a substantially homologous native DNA sequence. This invention also provides methods of using these transgenic animals for identifying therapeutic and other reagents that affect angiogenesis. Additionally provided are methods of using transgenic animals whose cells contain any donor genes as models for testing various reagents.
IPC 1-7
IPC 8 full level
A01K 67/027 (2006.01); A61K 45/00 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07K 14/71 (2006.01); C12N 15/09 (2006.01); C12N 15/85 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01)
CPC (source: EP)
A01K 67/0271 (2013.01); A01K 67/0275 (2013.01); A01K 67/0276 (2013.01); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07K 14/71 (2013.01); C12N 15/8509 (2013.01); A01K 2217/05 (2013.01); A01K 2217/072 (2013.01); A01K 2217/075 (2013.01); A01K 2227/105 (2013.01); A01K 2267/03 (2013.01); C07K 2319/00 (2013.01)
Citation (search report)
See references of WO 9918191A1
Designated contracting state (EPC)
AT BE CH DE DK ES FR GB IE IT LI NL SE
DOCDB simple family (publication)
WO 9918191 A1 19990415; AU 9598598 A 19990427; CA 2305045 A1 19990415; EP 1007652 A1 20000614; JP 2001519145 A 20011023
DOCDB simple family (application)
US 9820717 W 19981002; AU 9598598 A 19981002; CA 2305045 A 19981002; EP 98949716 A 19981002; JP 2000514989 A 19981002