EP 1009236 A4 20001025 - EVALUATION OF, DELIVERY OF, AND USE OF AGENTS TO TREAT HEART DISORDERS
Title (en)
EVALUATION OF, DELIVERY OF, AND USE OF AGENTS TO TREAT HEART DISORDERS
Title (de)
EVALUIERUNG, VERABREICHUNG UND VERWENDUNG VON MITTELN ZUR BEHANDLUNG VONHERZERKRANKUNGEN
Title (fr)
EVALUATION DES AGENTS ADAPTES AU TRAITEMENT DE CARDIOPATHIES, ADMINISTRATION ET UTILISATION DE TELS AGENTS
Publication
Application
Priority
- US 9814968 W 19980720
- US 5335697 P 19970722
Abstract (en)
[origin: WO9904636A1] The invention provides methods of evaluating a tratement for a heart disorder. The invention also provides methods of delivering a compound to the heart of a subject. A heart cell, into which has been introduced by somatic gene transfer, a nucleic acid which results in the expression of phospholamban, a heart tissue, into which has been introduced by somatic gene transfer, a nucleic acid which results in the expression of phospholamban and a heart, into which has been introduced by somatic gene transfer, a nucleic acid which results in the expression of phospholamban are also provided by the invention. Finally, the invention provides a method for treating a subject at risk for a heart disorder.
IPC 1-7
A01N 63/00; A01N 43/04; C12Q 1/68; C12N 15/64; C12N 5/00; C07H 21/04; G01N 33/50
IPC 8 full level
A61P 9/04 (2006.01); C07K 14/47 (2006.01); A61K 48/00 (2006.01)
CPC (source: EP)
A61P 9/04 (2017.12); C07K 14/47 (2013.01); C12N 15/1138 (2013.01); A01K 2217/075 (2013.01); A61K 48/00 (2013.01); C12N 2310/14 (2013.01); C12N 2799/022 (2013.01); C12N 2799/027 (2013.01)
Citation (search report)
- [PXA] HAJJAR, ROGER J. ET AL: "Modulation of ventricular function through gene transfer in vivo", PROC. NATL. ACAD. SCI. U. S. A. (1998), 95(9), 5251-5256, XP002141696
- [PA] NEUMANN, J. ET AL.: "Targeted overexpression of phospholamban to mouse atrium depresses Ca2+ transport and contractility", JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, vol. 30, no. 10, October 1998 (1998-10-01), pages 1991 - 2002, XP002141697
- [AP] HOIT, B.D. ET AL.: "Influence of transgenic overexpression of phospholamban on postextrasystolic potentation", JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, vol. 31, no. 11, November 1999 (1999-11-01), pages 2007 - 2015, XP002141698
- See references of WO 9904636A1
Designated contracting state (EPC)
CH DE ES FR GB LI
DOCDB simple family (publication)
WO 9904636 A1 19990204; WO 9904636 A9 19990429; CA 2297328 A1 19990204; EP 1009236 A1 20000621; EP 1009236 A4 20001025
DOCDB simple family (application)
US 9814968 W 19980720; CA 2297328 A 19980720; EP 98934656 A 19980720