Global Patent Index - EP 1009441 A1

EP 1009441 A1 2000-06-21 - METHOD FOR THE TREATMENT OF GRAFTS

Title (en)

METHOD FOR THE TREATMENT OF GRAFTS

Title (de)

VERFAHREN ZUR BEHANDLUNG VON TRANSPLANTATEN

Title (fr)

PROCEDE DE TRAITEMENT DES GREFFONS

Publication

EP 1009441 A1 (EN)

Application

EP 98939149 A

Priority

  • US 9815971 W
  • US 5438697 P

Abstract (en)

[origin: WO9906073A1] The present invention provides a method for treatment of grafts which comprises introducing a nucleic acid encoding an angiogenic agent into the cells of the graft. The graft may be treated ex vivo and then transplanted into the donor or may be treated after transplantation. The graft may be autologous, allogenic, xenogenic or a tissue engineered graft ("bio-artifical" organ). The nucleic acid may be introduced to the cultured cells used to form the tissue engineered graft. Expression of the angiogenic agent by the cells of the graft promotes growth of new blood vessels (angiogenesis) providing the graft with a blood supply thus increasing the chances for graft survival.

IPC 1-7 (main, further and additional classification)

A61K 48/00

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 38/18 (2006.01); A61K 48/00 (2006.01); A61P 37/06 (2006.01); A61K 38/00 (2006.01)

CPC (invention and additional information)

A61K 38/1866 (2013.01); A61K 35/36 (2013.01); A61K 48/00 (2013.01)

Combination set (CPC)

  1. A61K 35/36 + A61K 2300/00
  2. A61K 38/1866 + A61K 2300/00

Citation (search report)

See references of WO 9906073A1

Designated contracting state (EPC)

DE FR GB IT

EPO simple patent family

WO 9906073 A1 19990211; AU 8763898 A 19990222; CA 2298811 A1 19990211; EP 1009441 A1 20000621; JP 2001511462 A 20010814

INPADOC legal status


2003-08-20 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20030201

2000-06-21 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000229

2000-06-21 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): DE FR GB IT