Global Patent Index - EP 1009820 A1

EP 1009820 A1 2000-06-21 - TISSUE SPECIFIC PROMOTERS

Title (en)

TISSUE SPECIFIC PROMOTERS

Title (de)

GEWEBE SPEZIFISCHE PROMOTOREN

Title (fr)

PROMOTEURS SPECIFIQUES DE TISSU

Publication

EP 1009820 A1 (EN)

Application

EP 98901256 A

Priority

  • AU 9800057 W
  • AU PO492397 A

Abstract (en)

[origin: WO9833903A1] The present invention provides a genetic construct providing preferential expression in specific tissue of a coding sequence. The construct includes the following elements (1): a steroid responsive promoter from a tissue specific gene, (2) a coding sequence, and (3) an SV40 enhancer. The elements are arranged as follows: the steroid responsive promoter from the tissue specific gene being upstream of the coding sequence and the SV40 enhancer being 3' of the coding sequence, or the SV40 enhancer being upstream of the coding sequence and the steroid responsive promoter from the tissue specific gene being positioned between the SV40 enhancer and the coding sequence, or the steroid responsive promoter from the tissue specific gene being upstream of the coding sequence and the SV40 enhancer being positioned within an intron within the coding sequence. The promoter has a lowered level of steroid responsiveness in the construct than in its native state.

IPC 1-7 (main, further and additional classification)

C12N 15/11; C12N 15/62

IPC 8 full level (invention and additional information)

C12N 9/64 (2006.01); C12N 15/85 (2006.01)

CPC (invention and additional information)

C12N 9/6445 (2013.01); C12N 15/85 (2013.01); C12N 2830/008 (2013.01); C12N 2830/85 (2013.01)

Citation (search report)

See references of WO 9833903A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9833903 A1 19980806; AU PO492397 D0 19970227; CA 2279552 A1 19980806; CN 1250477 A 20000412; EP 1009820 A1 20000621

INPADOC legal status


2000-08-30 [18W] WITHDRAWN

- Date of withdrawal: 20000705

2000-06-21 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990816

2000-06-21 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE