EP 1009835 A2 20000621 - PROTEASE BASED GENE SWITCHING SYSTEM
Title (en)
PROTEASE BASED GENE SWITCHING SYSTEM
Title (de)
AUF PROTEASEN BASIERTES GEN-REGULIERUNGSSYSTEM
Title (fr)
SYSTEMES DE COMMUTATION DE GENES A BASE DE PROTEASES
Publication
Application
Priority
- GB 9802596 W 19980828
- GB 9718591 A 19970903
Abstract (en)
[origin: WO9911801A2] The present invention relates to materials and methods for protease-based gene switching systems, wherein a transcription factor is bound to a membrane via protease cleavage site. It also relates to the use of such materials and methods in the identification of substrates and inhibitors of proteases and in the design of altered specificity proteases.
IPC 1-7
IPC 8 full level
C12N 1/19 (2006.01); C12N 9/04 (2006.01); C12N 9/50 (2006.01); C12N 15/62 (2006.01); C12N 15/63 (2006.01); C12Q 1/37 (2006.01)
CPC (source: EP)
C12N 9/0006 (2013.01); C12N 9/503 (2013.01); C12N 15/62 (2013.01); C12N 15/63 (2013.01); C12Q 1/37 (2013.01); C07K 2319/00 (2013.01); C07K 2319/033 (2013.01); C07K 2319/50 (2013.01); C07K 2319/61 (2013.01); C07K 2319/71 (2013.01); C07K 2319/81 (2013.01)
Citation (search report)
See references of WO 9911801A2
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9911801 A2 19990311; WO 9911801 A3 19990610; EP 1009835 A2 20000621; GB 9718591 D0 19971105
DOCDB simple family (application)
GB 9802596 W 19980828; EP 98940421 A 19980828; GB 9718591 A 19970903