EP 1009848 A1 20000621 - METHOD FOR PRODUCING ENANTIOMER-FREE PHENYLACETYL CARBINOLES FROM ACETALDEHYDE AND BENZALDEHYDE IN THE PRESENCE OF PYRUVATE DECARBOXYLASE FROM ZYMOMONAS
Title (en)
METHOD FOR PRODUCING ENANTIOMER-FREE PHENYLACETYL CARBINOLES FROM ACETALDEHYDE AND BENZALDEHYDE IN THE PRESENCE OF PYRUVATE DECARBOXYLASE FROM ZYMOMONAS
Title (de)
VERFAHREN ZUR HERSTELLUNG VON ENANTIOMERENREINEN PHENYLACETYLCARBINOLEN AUS ACETALDEHYD UND BENZALDEHYD IN GEGENWART VON PYRUVATDECARBOXYLASE AUS ZYMOMONAS
Title (fr)
PROCEDE POUR LA PREPARATION DE PHENYLACETYLCARBINOLES ENANTIOMERIQUEMENT PURS A PARTIR D'ACETALDEHYDE ET DE BENZALDEHYDIE EN PRESENCE DE PYRUVATE-DECARBOXYLASE ISSUE DE ZYMOMONAS
Publication
Application
Priority
- DE 19736104 A 19970820
- EP 9804672 W 19980725
Abstract (en)
[origin: DE19736104A1] Preparation of entantiomerically pure phenylacetycarbinol derivatives (I) from acetaldehyde and benzaldehyde is carried out in the presence of pyruvate decarboxylase, which is obtained from Zymomonas mobilis. Preparation of entantiomerically pure phenylacetycarbinol derivatives of formula (I) comprises reacting acetaldehyde with the corresponding benzaldehyde (II) in the presence of pyruvate decarboxylase obtained from Zymomonas. The novelty comprises continuous or discontinuous addition of acetaldehyde to the reaction mixture, to ensure that the acetaldehyde concentration stays at 20-50 mMol/l: R = H, F, Cl or Br.
IPC 1-7
IPC 8 full level
CPC (source: EP)
Citation (search report)
See references of WO 9909195A1
Designated contracting state (EPC)
CH DE DK ES FR GB IT LI NL
DOCDB simple family (publication)
DE 19736104 A1 19990225; AR 016832 A1 20010801; AU 8732798 A 19990308; EP 1009848 A1 20000621; JP 2001514899 A 20010918; WO 9909195 A1 19990225
DOCDB simple family (application)
DE 19736104 A 19970820; AR P980104093 A 19980819; AU 8732798 A 19980725; EP 9804672 W 19980725; EP 98938706 A 19980725; JP 2000509857 A 19980725