Global Patent Index - EP 1009848 A1

EP 1009848 A1 2000-06-21 - METHOD FOR PRODUCING ENANTIOMER-FREE PHENYLACETYL CARBINOLES FROM ACETALDEHYDE AND BENZALDEHYDE IN THE PRESENCE OF PYRUVATE DECARBOXYLASE FROM ZYMOMONAS

Title (en)

METHOD FOR PRODUCING ENANTIOMER-FREE PHENYLACETYL CARBINOLES FROM ACETALDEHYDE AND BENZALDEHYDE IN THE PRESENCE OF PYRUVATE DECARBOXYLASE FROM ZYMOMONAS

Title (de)

VERFAHREN ZUR HERSTELLUNG VON ENANTIOMERENREINEN PHENYLACETYLCARBINOLEN AUS ACETALDEHYD UND BENZALDEHYD IN GEGENWART VON PYRUVATDECARBOXYLASE AUS ZYMOMONAS

Title (fr)

PROCEDE POUR LA PREPARATION DE PHENYLACETYLCARBINOLES ENANTIOMERIQUEMENT PURS A PARTIR D'ACETALDEHYDE ET DE BENZALDEHYDIE EN PRESENCE DE PYRUVATE-DECARBOXYLASE ISSUE DE ZYMOMONAS

Publication

EP 1009848 A1 (DE)

Application

EP 98938706 A

Priority

  • DE 19736104 A
  • EP 9804672 W

Abstract (en)

[origin: DE19736104A1] Preparation of entantiomerically pure phenylacetycarbinol derivatives (I) from acetaldehyde and benzaldehyde is carried out in the presence of pyruvate decarboxylase, which is obtained from Zymomonas mobilis. Preparation of entantiomerically pure phenylacetycarbinol derivatives of formula (I) comprises reacting acetaldehyde with the corresponding benzaldehyde (II) in the presence of pyruvate decarboxylase obtained from Zymomonas. The novelty comprises continuous or discontinuous addition of acetaldehyde to the reaction mixture, to ensure that the acetaldehyde concentration stays at 20-50 mMol/l: R = H, F, Cl or Br.

IPC 1-7 (main, further and additional classification)

C12P 7/26

IPC 8 full level (invention and additional information)

C12N 9/88 (2006.01); C12P 7/26 (2006.01)

CPC (invention and additional information)

C12N 9/88 (2013.01); C12P 7/26 (2013.01)

Designated contracting state (EPC)

CH DE DK ES FR GB IT LI NL

EPO simple patent family

DE 19736104 A1 19990225; AR 016832 A1 20010801; AU 8732798 A 19990308; EP 1009848 A1 20000621; JP 2001514899 A 20010918; WO 9909195 A1 19990225

INPADOC legal status


2001-11-21 [18W] WITHDRAWN

- Date of withdrawal: 20010925

2000-06-21 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000205

2000-06-21 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): CH DE DK ES FR GB IT LI NL