EP 1011656 A2 20000628 - A METHOD FOR TREATING TENSION-TYPE HEADACHE
Title (en)
A METHOD FOR TREATING TENSION-TYPE HEADACHE
Title (de)
METHODEN ZUR BEHANDLUNG VON ANSPANNUNGSBEDINGTEN KOPFSCHMERZEN
Title (fr)
PROCEDE DE TRAITEMENT DE CEPHALEES DU TYPE PAR TENSION NERVEUSE
Publication
Application
Priority
- DK 9700502 W 19971104
- DK 124396 A 19961105
Abstract (en)
[origin: WO9819674A2] Tension-type headache is treated by interacting with neuronal transmission in relation to pain in connection with headache in a way which prevents or decreases sensitization of second order nociceptive neurons. In particular, treatment is performed by administration of an effective amount of a substance which prevents or decreases central sensitization. Important examples of such substances are substances which interact with glutamate neurotransmission, such as glutamate receptor antagonists, such as NMDA receptor antagonists, such as MK-801 or Amitriptylline or Imipramine or Desipramine or Mirtazaprine or Venlafaxine. Other examples are substances which interact with nitric oxide, such as nitric oxide synthase (NOS) inhibitors, such as L-NMMA or L-NAME or L-NIO or L-NNA. According to a broader aspect of the invention tension-type headache is treated by administration of substances which are effective in preventing or decreasing pain in connection with tension-type headache, such as the substances mentioned above. An additional aspect of the invention relates to treatment of tension-type headache by administration of substances which substantially inhibit the activity of nitric oxide synthase (NOS), such as NOS inhibitors, such as L-NMMA or L-NAME or L-NIO or L-NNA.
IPC 1-7
IPC 8 full level
A61K 31/195 (2006.01); A61K 38/08 (2019.01); A61K 31/00 (2006.01); A61K 31/13 (2006.01); A61K 31/137 (2006.01); A61K 31/138 (2006.01); A61K 31/155 (2006.01); A61K 31/165 (2006.01); A61K 31/167 (2006.01); A61K 31/196 (2006.01); A61K 31/197 (2006.01); A61K 31/198 (2006.01); A61K 31/223 (2006.01); A61K 31/27 (2006.01); A61K 31/33 (2006.01); A61K 31/40 (2006.01); A61K 31/4015 (2006.01); A61K 31/404 (2006.01); A61K 31/407 (2006.01); A61K 31/416 (2006.01); A61K 31/4164 (2006.01); A61K 31/4166 (2006.01); A61K 31/4168 (2006.01); A61K 31/4174 (2006.01); A61K 31/42 (2006.01); A61K 31/428 (2006.01); A61K 31/437 (2006.01); A61K 31/439 (2006.01); A61K 31/4409 (2006.01); A61K 31/445 (2006.01); A61K 31/4465 (2006.01); A61K 31/451 (2006.01); A61K 31/4525 (2006.01); A61K 31/4535 (2006.01); A61K 31/454 (2006.01); A61K 31/4545 (2006.01); A61K 31/455 (2006.01); A61K 31/47 (2006.01); A61K 31/4704 (2006.01); A61K 31/4725 (2006.01); A61K 31/485 (2006.01); A61K 31/495 (2006.01); A61K 31/496 (2006.01); A61K 31/498 (2006.01); A61K 31/4985 (2006.01); A61K 31/505 (2006.01); A61K 31/519 (2006.01); A61K 31/522 (2006.01); A61K 31/53 (2006.01); A61K 31/54 (2006.01); A61K 31/55 (2006.01); A61K 31/551 (2006.01); A61K 31/5517 (2006.01); A61K 31/58 (2006.01); A61K 31/66 (2006.01); A61K 31/675 (2006.01); A61K 31/70 (2006.01); A61K 35/00 (2006.01); A61K 38/05 (2006.01)
CPC (source: EP US)
A61K 31/00 (2013.01 - EP); A61K 31/13 (2013.01 - EP); A61K 31/137 (2013.01 - EP); A61K 31/138 (2013.01 - EP); A61K 31/155 (2013.01 - EP); A61K 31/165 (2013.01 - EP); A61K 31/167 (2013.01 - EP); A61K 31/195 (2013.01 - EP); A61K 31/196 (2013.01 - EP); A61K 31/197 (2013.01 - EP); A61K 31/198 (2013.01 - EP); A61K 31/223 (2013.01 - EP); A61K 31/27 (2013.01 - EP); A61K 31/33 (2013.01 - EP); A61K 31/4015 (2013.01 - EP); A61K 31/404 (2013.01 - EP); A61K 31/407 (2013.01 - EP); A61K 31/416 (2013.01 - EP); A61K 31/4164 (2013.01 - EP); A61K 31/4166 (2013.01 - EP); A61K 31/4168 (2013.01 - EP); A61K 31/4174 (2013.01 - EP); A61K 31/42 (2013.01 - EP); A61K 31/428 (2013.01 - EP); A61K 31/437 (2013.01 - EP); A61K 31/439 (2013.01 - EP); A61K 31/4409 (2013.01 - EP); A61K 31/445 (2013.01 - EP); A61K 31/4465 (2013.01 - EP); A61K 31/451 (2013.01 - EP); A61K 31/4525 (2013.01 - EP); A61K 31/4535 (2013.01 - EP); A61K 31/454 (2013.01 - EP); A61K 31/4545 (2013.01 - EP); A61K 31/455 (2013.01 - EP); A61K 31/47 (2013.01 - EP); A61K 31/4704 (2013.01 - EP); A61K 31/4725 (2013.01 - EP); A61K 31/485 (2013.01 - EP); A61K 31/495 (2013.01 - EP); A61K 31/496 (2013.01 - EP); A61K 31/498 (2013.01 - EP); A61K 31/4985 (2013.01 - EP); A61K 31/519 (2013.01 - EP); A61K 31/522 (2013.01 - EP); A61K 31/53 (2013.01 - EP); A61K 31/54 (2013.01 - EP); A61K 31/55 (2013.01 - EP); A61K 31/551 (2013.01 - EP); A61K 31/5517 (2013.01 - EP); A61K 31/58 (2013.01 - EP); A61K 31/66 (2013.01 - EP); A61K 31/662 (2013.01 - EP); A61K 31/675 (2013.01 - EP); A61K 31/7076 (2013.01 - EP); A61K 38/05 (2013.01 - EP); A61K 38/08 (2013.01 - EP US); A61P 25/00 (2017.12 - EP)
Citation (search report)
See references of WO 9819674A2
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
Designated extension state (EPC)
AL LT LV MK RO SI
DOCDB simple family (publication)
WO 9819674 A2 19980514; WO 9819674 A3 19980716; AU 4863297 A 19980529; AU 734490 B2 20010614; CA 2270531 A1 19980514; CA 2270531 C 20110830; EP 1011656 A2 20000628; EP 1132082 A1 20010912; EP 1829539 A2 20070905; EP 1829539 A3 20080220
DOCDB simple family (application)
DK 9700502 W 19971104; AU 4863297 A 19971104; CA 2270531 A 19971104; EP 00204625 A 19971104; EP 07107912 A 19971104; EP 97911150 A 19971104