EP 1011671 A1 20000628 - SUBSTANCE DEPENDENCE TREATMENT USING OPIATE ANTAGONISTS AND SEROTONIN COMPOUNDS
Title (en)
SUBSTANCE DEPENDENCE TREATMENT USING OPIATE ANTAGONISTS AND SEROTONIN COMPOUNDS
Title (de)
ENTWÖHNUNGSTHERAPIE MIT OPIAT- UND SEROTONINANTAGONISTEN
Title (fr)
TRAITEMENT DE LA DEPENDANCE A CERTAINES SUBSTANCES A L'AIDE DE COMPOSES D'ANTAGONISTES D'OPIACES ET DE SEROTONINE
Publication
Application
Priority
- US 9810289 W 19980519
- US 4616297 P 19970520
Abstract (en)
[origin: WO9852565A1] Patients are treated for alcohol, marijuana, cocaine, opiate and polysubstance dependency by administration of combination of an effective amount of an opioid antagonist such as nalmefene, naloxone, naltrexone, or a mixture of any of these, and a serotonergic medication, such as sertraline, fluoxetine, paroxetine, fluvoxamine, or odansetron. Administration of an effective amount of an opioid antagonist alone helps to prevent relapse after detoxification is complete, and addition of the serotonergic medication increases the effectiveness, decreases the side effects of the opioid antagonist, and also helps relieve effects of withdrawal.
IPC 1-7
IPC 8 full level
A61K 31/135 (2006.01); A61K 31/485 (2006.01); A61K 45/08 (2006.01); A61P 25/36 (2006.01)
CPC (source: EP)
A61K 31/485 (2013.01); A61P 25/36 (2017.12)
Citation (search report)
See references of WO 9852565A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9852565 A1 19981126; AU 7582498 A 19981211; CA 2290788 A1 19981126; EP 1011671 A1 20000628; JP 2002508753 A 20020319
DOCDB simple family (application)
US 9810289 W 19980519; AU 7582498 A 19980519; CA 2290788 A 19980519; EP 98923558 A 19980519; JP 55056398 A 19980519