Global Patent Index - EP 1012245 A1

EP 1012245 A1 2000-06-28 - SURFACE EXPRESSION SYSTEM OF HEPATITIS B VIRUS SURFACE ANTIGEN AND CORE ANTIGEN OF HEPATITIS C VIRUS BY USING ICE-NUCLEATION PROTEIN

Title (en)

SURFACE EXPRESSION SYSTEM OF HEPATITIS B VIRUS SURFACE ANTIGEN AND CORE ANTIGEN OF HEPATITIS C VIRUS BY USING ICE-NUCLEATION PROTEIN

Title (de)

OBERFLÄCHENEXPRESSIONSSYSTEM VON HEPATITIS B VIRUS OBERFLÄCHENANTIGEN UND KERNANTIGEN VON HEPATITIS C VIRUS UNTER VERWENDUNG VON EIS-KERN PROTEIN

Title (fr)

SYSTEME D'EXPRESSION DE SURFACE DE L'ANTIGENE DE SURFACE ET DE L'ANTIGENE CAPSIDIQUE DU VIRUS DE L'HEPATITE B AU MOYEN D'UNE PROTEINE DE NUCLEATION DE LA GLACE

Publication

EP 1012245 A1 (EN)

Application

EP 99928212 A

Priority

  • KR 9900339 W
  • KR 19980024062 A
  • KR 19990024244 A

Abstract (en)

[origin: WO9967366A1] Disclosed is the expression of foreign proteins on the surfaces of microorganisms. Antigenic proteins originating from pathogens, including the surface HBsAg and the core antigen of HCV, can be effectively expressed on microbial cell surfaces by use of ice-nucleation proteins. The microbes which have the antigenic proteins on their surfaces can be used as attenuated, complex live vaccines.

IPC 1-7 (main, further and additional classification)

C12N 7/01; C12N 1/21; C12N 15/31

IPC 8 full level (invention and additional information)

C12N 15/63 (2006.01); C07K 14/02 (2006.01); C07K 14/21 (2006.01); C12N 1/21 (2006.01); C12N 7/01 (2006.01); C12N 15/70 (2006.01); A61K 39/00 (2006.01)

CPC (invention and additional information)

C07K 14/005 (2013.01); C07K 14/21 (2013.01); C12N 15/70 (2013.01); A61K 39/00 (2013.01); C07K 2319/00 (2013.01); C12N 2730/10122 (2013.01)

Citation (search report)

See references of WO 9967366A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9967366 A1 19991229; AU 4531899 A 20000110; EP 1012245 A1 20000628; KR 20000006463 A 20000125

INPADOC legal status


2004-04-14 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20031014

2003-05-21 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20030403

2000-08-09 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: GREEN CROSS VACCINE CORPORATION

2000-08-09 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTEC

2000-08-09 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: KIM, CHUL-JOONG

2000-06-28 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000320

2000-06-28 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE