Global Patent Index - EP 1012269 A2

EP 1012269 A2 2000-06-28 - P13 ANTIGENS FROM BORRELIA

Title (en)

P13 ANTIGENS FROM BORRELIA

Title (de)

P13 ANTIGENEN VON BORRELIA

Title (fr)

ANTIGENES P13 PROVENANT DE BORRELIA

Publication

EP 1012269 A2 (EN)

Application

EP 98940504 A

Priority

  • DK 104197 A
  • IB 9801424 W
  • US 5903697 P

Abstract (en)

[origin: WO9912960A2] The invention relates to an isolated nucleic acid fragment which encodes a polypeptide fragment which exhibits a substantial immunological reactivity with a rabbit polyclonal antibody raised against a polypeptide having an apparent molecular weight of 13 kDa as determined by SDS-PAGE followed by vizualization, said polypeptide being derived from Borrelia burgdorferi B313 and being encoded by the nucleotide sequence of SEQ ID NO:18, said rabbit polyclonal antibody exhibiting substantially no immunological reactivity with proteins from at least 95 % of spirochaetes randomly selected from the group consisting of Borrelia hermsii, Borrelia crocidurae, Borrelia anserina, and Borrelia hispanica, and/or hybridizes readily under highly stringent hybridization conditions with a DNA fragment having a nucleotide sequence selected from the group consisting of SEQ ID NO:18, SEQ ID NO:20, and SEQ ID NO:22, or with a DNA fragment complementary thereto, but exhibits no substantial hybridization when the hybridization conditions are highly stringent with genomic DNA from at least 95 % of spirochaetes randomly selected from the group consisting of Borrelia hermsii, Borrelia crocidurae, Borrelia anserina, and Borrelia hispanica. Furthermore, the invention relates to polypeptide fragments, vectors, transformed cells, and cell lines, a method of preparing a polypeptide fragment and, vaccines as well as diagnostic compositions and kits.

IPC 1-7 (main, further and additional classification)

C12N 15/11; A61K 39/002; C07K 14/20; C12N 15/62; C12N 15/63; C12Q 1/68; G01N 33/569

IPC 8 full level (invention and additional information)

C07K 14/20 (2006.01); A61K 39/00 (2006.01)

CPC (invention and additional information)

C07K 14/20 (2013.01); A61K 39/00 (2013.01); C07K 2319/00 (2013.01)

Citation (search report)

See references of WO 9912960A3

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9912960 A2 19990318; WO 9912960 A3 19990527; AU 8881198 A 19990329; CA 2300365 A1 19990318; EP 1012269 A2 20000628

INPADOC legal status


2005-04-13 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20041012

2004-05-12 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20040330

2002-06-26 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: SYMBICOM AB

2000-06-28 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000410

2000-06-28 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A2

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE