Global Patent Index - EP 1012335 A1

EP 1012335 A1 2000-06-28 - METHODS AND COMPOSITIONS FOR DETECTION OR QUANTIFICATION OF NUCLEIC ACID SPECIES

Title (en)

METHODS AND COMPOSITIONS FOR DETECTION OR QUANTIFICATION OF NUCLEIC ACID SPECIES

Title (de)

ERFAHREN UND ZUSAMMENSETZUNGEN ZUR DETEKTION ODER QUANTIFIZIERUNG VON NUKLEINSÄURESPEZIES

Title (fr)

PROCEDES ET COMPOSITIONS DE DETECTION OU DE QUANTIFICATION D'ESPECES D'ACIDES NUCLEIQUES

Publication

EP 1012335 A1 (EN)

Application

EP 98940915 A

Priority

  • US 9816966 W
  • US 91288597 A
  • US 94777997 A
  • US 95936597 A

Abstract (en)

[origin: WO9909217A1] The present invention provides a method for detecting a target nucleic acid species using an array of probes affixed to a substrate and a plurality of labeled probes. The invention also relates to oligonucleotide probes attached to discrete particles wherein the particles can be grouped into a plurality of sets based on a physical property. A different probe is attached to the discrete particles of each set, and the identity of the probe is determined by identifying the discrete particles from their physical property. The invention further relates to methods using agents which destabilize the binding of complementary polynucleotide strands (decrease the binding energy) or increase stability of binding between complementary polynucleotide strands (increase the binding energy). The figure is an illustration of an apparatus for mass producing probe arrays.

IPC 1-7 (main, further and additional classification)

C12P 19/34; C12Q 1/68

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); C12P 19/34 (2006.01); C12Q 1/68 (2006.01); G01N 33/53 (2006.01); G01N 37/00 (2006.01); C40B 40/06 (2006.01); C40B 60/14 (2006.01)

CPC (invention and additional information)

C12Q 1/6837 (2013.01); C12Q 1/6874 (2013.01); B01J 2219/00317 (2013.01); B01J 2219/00511 (2013.01); B01J 2219/00608 (2013.01); B01J 2219/0061 (2013.01); B01J 2219/00612 (2013.01); B01J 2219/00619 (2013.01); B01J 2219/00621 (2013.01); B01J 2219/00626 (2013.01); B01J 2219/0063 (2013.01); B01J 2219/00637 (2013.01); B01J 2219/00641 (2013.01); B01J 2219/00648 (2013.01); B01J 2219/00659 (2013.01); B01J 2219/00722 (2013.01); C40B 40/06 (2013.01); C40B 60/14 (2013.01)

Combination set (CPC)

C12Q 1/6874 + C12Q 2525/107 + C12Q 2565/518

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9909217 A1 19990225; AU 8908198 A 19990308; CA 2300940 A1 19990225; CN 1273609 A 20001115; EP 1012335 A1 20000628; EP 1012335 A4 20040609; JP 2001514906 A 20010918

INPADOC legal status


2005-09-28 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20050322

2004-12-22 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20041109

2004-06-09 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20040426

2004-06-09 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12P 19/34 A

2004-06-09 [RIC1] CLASSIFICATION (CORRECTION)

- IPC: 7C 12Q 1/68 B

2000-06-28 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000306

2000-06-28 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE