Global Patent Index - EP 1014956 A1

EP 1014956 A1 20000705 - METHODS OF USING INTEGRIN MODULATORS

Title (en)

METHODS OF USING INTEGRIN MODULATORS

Title (de)

VERFAHREN ZUR VERWENDUNG VON INTEGRIN MODULATOREN

Title (fr)

PROCEDES D'UTILISATION DE MODULATEURS DES INTEGRINES

Publication

EP 1014956 A1 20000705 (EN)

Application

EP 97902935 A 19970113

Priority

  • US 9700583 W 19970113
  • US 58519096 A 19960111
  • US 58405296 A 19960111
  • US 58518796 A 19960111
  • US 58518896 A 19960111
  • US 58403896 A 19960111
  • US 69889396 A 19960816

Abstract (en)

[origin: WO9725031A1] The invention provides methods of treating a variety of diseases and conditions by administering an effective amount of an integrin modulating agent, as further defined and specified herein, to an animal suffering from one of the diseases or conditions. The preferred integrin modulating agents are ajoene and disintegrins, variants and analogs of disintegrins. In particular, the invention provides: (1) a method of treating inflammation; (2) methods of treating and preventing viral infections; (3) a method of treating shock; (4) a method of treating arthritis; (5) a method of contraception; (6) a method of suppressing immune responses; (7) a method of treating an autoimmune disease; (8) a method of inhibiting undesirable integrin-mediated cell-cell fusion; (9) a method of inhibiting the formation of lesions; (10) a method of treating psoriasis; (11) a method of treating atherosclerosis; (12) a method of treating diseases or conditions involving a plurality of integrin-dependent etiopathogenetic mechanisms; and (13) a method of inhibiting the transfer of genetic material.

IPC 1-7

A61K 31/10

IPC 8 full level

A61K 31/00 (2006.01); A61K 31/105 (2006.01); A61K 31/145 (2006.01); A61K 38/17 (2006.01); A61K 38/39 (2006.01)

CPC (source: EP)

A61K 31/00 (2013.01); A61K 31/105 (2013.01); A61K 31/145 (2013.01); A61K 38/1703 (2013.01); A61K 38/39 (2013.01)

Designated contracting state (EPC)

AT CH DE DK ES FR GB GR IT LI NL PT SE

DOCDB simple family (publication)

WO 9725031 A1 19970717; AU 1699397 A 19970801; EP 1014956 A1 20000705; EP 1014956 A4 20011107

DOCDB simple family (application)

US 9700583 W 19970113; AU 1699397 A 19970113; EP 97902935 A 19970113