Global Patent Index - EP 1014956 A1

EP 1014956 A1 2000-07-05 - METHODS OF USING INTEGRIN MODULATORS

Title (en)

METHODS OF USING INTEGRIN MODULATORS

Title (de)

VERFAHREN ZUR VERWENDUNG VON INTEGRIN MODULATOREN

Title (fr)

PROCEDES D'UTILISATION DE MODULATEURS DES INTEGRINES

Publication

EP 1014956 A1 (EN)

Application

EP 97902935 A

Priority

  • US 9700583 W
  • US 58519096 A
  • US 58405296 A
  • US 58518796 A
  • US 58518896 A
  • US 58403896 A
  • US 69889396 A

Abstract (en)

[origin: WO9725031A1] The invention provides methods of treating a variety of diseases and conditions by administering an effective amount of an integrin modulating agent, as further defined and specified herein, to an animal suffering from one of the diseases or conditions. The preferred integrin modulating agents are ajoene and disintegrins, variants and analogs of disintegrins. In particular, the invention provides: (1) a method of treating inflammation; (2) methods of treating and preventing viral infections; (3) a method of treating shock; (4) a method of treating arthritis; (5) a method of contraception; (6) a method of suppressing immune responses; (7) a method of treating an autoimmune disease; (8) a method of inhibiting undesirable integrin-mediated cell-cell fusion; (9) a method of inhibiting the formation of lesions; (10) a method of treating psoriasis; (11) a method of treating atherosclerosis; (12) a method of treating diseases or conditions involving a plurality of integrin-dependent etiopathogenetic mechanisms; and (13) a method of inhibiting the transfer of genetic material.

IPC 1-7 (main, further and additional classification)

A61K 31/10

IPC 8 full level (invention and additional information)

A61K 31/00 (2006.01); A61K 31/105 (2006.01); A61K 31/145 (2006.01); A61K 38/17 (2006.01); A61K 38/39 (2006.01)

CPC (invention and additional information)

A61K 38/39 (2013.01); A61K 31/00 (2013.01); A61K 31/105 (2013.01); A61K 31/145 (2013.01); A61K 38/1703 (2013.01)

Designated contracting state (EPC)

AT CH DE DK ES FR GB GR IT LI NL PT SE

EPO simple patent family

WO 9725031 A1 19970717; AU 1699397 A 19970801; EP 1014956 A1 20000705; EP 1014956 A4 20011107

INPADOC legal status


2004-01-14 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030617

2002-04-24 [17Q] FIRST EXAMINATION REPORT

- Effective date: 20020308

2001-11-07 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20010919

2001-11-07 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT CH DE DK ES FR GB GR IT LI NL PT SE

2000-07-05 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19981013

2000-07-05 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT CH DE DK ES FR GB GR IT LI NL PT SE