Global Patent Index - EP 1014977 A4

EP 1014977 A4 2000-07-05 - DIAGNOSIS OF MIGRAINE WITH AURA, DEPRESSION AND ANXIETY FROM ALLELIC VARIATIONS IN DOPAMINERGIC GENES

Title (en)

DIAGNOSIS OF MIGRAINE WITH AURA, DEPRESSION AND ANXIETY FROM ALLELIC VARIATIONS IN DOPAMINERGIC GENES

Title (de)

DIAGNOSE VON MIGRAINE BEGLEITET VON AURA, DEPRESSION UND ANGST DURCH ALLELVARIATIONEN IN DOPAMINERGEN GENEN

Title (fr)

METHODES DE DIAGNOSTIC DE LA MIGRAINE ACCOMPAGNEE D'AURA, DE DEPRESSION ET D'ANGOISSE, A PARTIR DE VARIATIONS ALLELIQUES DE GENES DOPAMINERGIQUES

Publication

EP 1014977 A4 (EN)

Application

EP 97938536 A

Priority

  • US 9714830 W
  • US 2439996 P
  • US 3609197 P

Abstract (en)

[origin: WO9807426A1] The invention provides methods of diagnosing a syndrome characterized by symptoms of migraine with aura, depression and/or anxiety. Diagnosis entails detecting a variant form of one or more dopaminergic genes, such as DRD1, DRD2, DRD3 and DAT. Methods of screening for therapeutic agents effective to treat the syndrome and methods of treatment are also provided.

IPC 1-7 (main, further and additional classification)

A61K 31/445

IPC 8 full level (invention and additional information)

C12N 15/09 (2006.01); A61K 31/135 (2006.01); A61K 31/166 (2006.01); A61K 31/38 (2006.01); A61K 31/382 (2006.01); A61K 31/40 (2006.01); A61K 31/445 (2006.01); A61K 31/454 (2006.01); A61K 31/495 (2006.01); A61K 31/496 (2006.01); A61K 31/519 (2006.01); A61K 31/5377 (2006.01); A61K 31/5415 (2006.01); A61K 31/5513 (2006.01); A61K 31/553 (2006.01); A61K 31/711 (2006.01); A61K 45/00 (2006.01); A61P 25/06 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C12Q 1/6883 (2013.01); A61K 31/135 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/156 (2013.01); C12Q 2600/172 (2013.01)

Citation (search report)

  • [T] PEROUTKA S.J.: "Dopamine and migraine", NEUROLOGY, vol. 4, no. 3, September 1997 (1997-09-01), pages 650 - 656, XP002118937
  • See also references of WO 9807426A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9807426 A1 19980226; AU 4083797 A 19980306; AU 737893 B2 20010906; CA 2263149 A1 19980226; EP 1014977 A1 20000705; EP 1014977 A4 20000705; JP 2001527520 A 20011225

INPADOC legal status


2003-09-03 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030301

2000-07-05 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990322

2000-07-05 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 19991102

2000-07-05 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-07-05 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE