Global patent index - EP 1014984 A1

EP 1014984 A1 2000-07-05 - INHIBITORS OF PRENYL-PROTEIN TRANSFERASE

Title (en)

INHIBITORS OF PRENYL-PROTEIN TRANSFERASE

Title (de)

PRENYL-PROTEIN TRANSFERASE INHIBITOREN

Title (fr)

INHIBITEURS DE PRENYL-PROTEINE-TRANSFERASES

Publication

EP 1014984 A1 (EN)

Application

EP 98943406 A

Priority

  • GB 9800975 A
  • US 9817696 W
  • US 5708097 P

Abstract (en)

[origin: WO9909985A1] The present invention is directed to compounds which inhibit prenyl-protein transferases, farnesyl-protein transferase and geranylgeranyl-protein transferase type I, and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and geranylgeranyl-protein transferase type I and the prenylation of the oncogene protein RAS.

IPC 1-7 (main, further and additional classification)

A61K 31/495; C07D 403/06

IPC 8 full level (invention and additional information)

A61K 31/496 (2006.01); A61P 9/00 (2006.01); A61P 13/12 (2006.01); A61P 27/02 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 403/06 (2006.01)

CPC (invention and additional information)

C07D 403/06 (2013.01)

Citation (search report)

See references of WO 9909985A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

EPO simple patent family

WO 9909985 A1 19990304; AU 741725 B2 20011206; AU 9121398 A 19990316; CA 2301770 A1 19990304; EP 1014984 A1 20000705; JP 2001513561 A 20010904

INPADOC legal status

2003-10-01 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20030203

2000-07-05 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000327

2000-07-05 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE

2000-07-05 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Ref Legal Event Code: AX

- Free Format Text: AL PAYMENT 20000327;LT PAYMENT 20000327;LV PAYMENT 20000327;MK PAYMENT 20000327;RO PAYMENT 20000327;SI PAYMENT 20000327