EP 1014984 A1 20000705 - INHIBITORS OF PRENYL-PROTEIN TRANSFERASE
Title (en)
INHIBITORS OF PRENYL-PROTEIN TRANSFERASE
Title (de)
PRENYL-PROTEIN TRANSFERASE INHIBITOREN
Title (fr)
INHIBITEURS DE PRENYL-PROTEINE-TRANSFERASES
Publication
Application
Priority
- GB 9800975 A 19980116
- US 9817696 W 19980826
- US 5708097 P 19970827
Abstract (en)
[origin: WO9909985A1] The present invention is directed to compounds which inhibit prenyl-protein transferases, farnesyl-protein transferase and geranylgeranyl-protein transferase type I, and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and geranylgeranyl-protein transferase type I and the prenylation of the oncogene protein RAS.
IPC 1-7
IPC 8 full level
A61K 31/496 (2006.01); A61P 9/00 (2006.01); A61P 13/12 (2006.01); A61P 27/02 (2006.01); A61P 31/12 (2006.01); A61P 35/00 (2006.01); A61P 43/00 (2006.01); C07D 403/06 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 13/12 (2017.12); A61P 27/02 (2017.12); A61P 31/12 (2017.12); A61P 35/00 (2017.12); A61P 43/00 (2017.12); C07D 403/06 (2013.01)
Citation (search report)
See references of WO 9909985A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9909985 A1 19990304; AU 741725 B2 20011206; AU 9121398 A 19990316; CA 2301770 A1 19990304; EP 1014984 A1 20000705; JP 2001513561 A 20010904
DOCDB simple family (application)
US 9817696 W 19980826; AU 9121398 A 19980826; CA 2301770 A 19980826; EP 98943406 A 19980826; JP 2000507375 A 19980826