EP 1014994 A1 20000705 - PHOSPHONO-CARBOXYLATE COMPOUNDS FOR TREATING AMYLOIDOSIS
Title (en)
PHOSPHONO-CARBOXYLATE COMPOUNDS FOR TREATING AMYLOIDOSIS
Title (de)
PHOSPHONOCARBOXYLATVERBINDUNGEN ZUR BEHANDLUNG VON AMYLOIDOSYS
Title (fr)
COMPOSES DE PHOSPHONO-CARBOXYLATE CONCUS POUR LE TRAITEMENT DE L'AMYLOSE
Publication
Application
Priority
- IB 9800967 W 19980410
- US 91257497 A 19970818
- US 7444598 P 19980211
Abstract (en)
[origin: WO9908685A1] Therapeutic compounds and methods for modulating amyloid deposition in a subject, whatever its clinical setting, are described. Amyloid deposition is modulated by the administration to a subject of an effective amount of a therapeutic compound comprising a phosphonate group and a carboxylate group, a congener thereof, or a pharmaceutically acceptable salt or ester thereof. In preferred embodiments, an interaction between an amyloidogenic protein and a basement membrane constituent is modulated.
IPC 1-7
IPC 8 full level
A61K 31/66 (2006.01); A61K 31/675 (2006.01); A61P 25/00 (2006.01); A61P 43/00 (2006.01); C07F 9/40 (2006.01)
CPC (source: EP)
A61K 31/662 (2013.01); A61K 31/675 (2013.01); A61P 3/00 (2017.12); A61P 9/00 (2017.12); A61P 25/00 (2017.12); A61P 25/28 (2017.12); A61P 43/00 (2017.12); C07F 9/4065 (2013.01)
Citation (search report)
See references of WO 9908685A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9908685 A1 19990225; CA 2300910 A1 19990225; CA 2300910 C 20080226; EP 1014994 A1 20000705; IL 134619 A0 20010430; JP 2001515039 A 20010918; NZ 550116 A 20080328
DOCDB simple family (application)
IB 9800967 W 19980410; CA 2300910 A 19980410; EP 98966963 A 19980410; IL 13461998 A 19980410; JP 2000509424 A 19980410; NZ 55011698 A 19980410