EP 1015453 A1 20000705 - 3-(IODOPHENOXYMETHYL) CARBAPENEM ANTIBACTERIALS
Title (en)
3-(IODOPHENOXYMETHYL) CARBAPENEM ANTIBACTERIALS
Title (de)
ANTIBAKTERIELLE 3-(IODOPHENOXYMETHYL)CARBAPENEM
Title (fr)
ANTIBACTERIENS DU TYPE 3-(IODOPHENOXYMETHYL) CARBAPENEM
Publication
Application
Priority
- GB 9815806 A 19980721
- US 9818578 W 19980904
- US 5822397 P 19970909
Abstract (en)
[origin: WO9912928A1] The present invention relates to carbapenem antibacterial agents in which the carbapenem nucleus is substituted at the 2-position with an iodo-substituted phenyl linked through a CH2-O- group. The compounds of the invention are represented by formula (I). Salts and hydrates thereof are included. The iodo-substituted phenyl ring is further substituted with various substituent groups including at least one cationic group. Pharmaceutical compositions and methods of treatment are also included.
IPC 1-7
IPC 8 full level
A61K 31/397 (2006.01); A61K 31/407 (2006.01); A61K 31/4178 (2006.01); A61K 31/4439 (2006.01); A61K 31/499 (2006.01); A61P 31/04 (2006.01); C07D 477/00 (2006.01); C07D 477/14 (2006.01); C07D 487/08 (2006.01)
CPC (source: EP)
A61P 31/04 (2017.12); C07D 477/14 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU NL PT SE
DOCDB simple family (publication)
WO 9912928 A1 19990318; AU 732335 B2 20010412; AU 9223698 A 19990329; CA 2302009 A1 19990318; EP 1015453 A1 20000705; EP 1015453 A4 20010919; JP 2003517427 A 20030527
DOCDB simple family (application)
US 9818578 W 19980904; AU 9223698 A 19980904; CA 2302009 A 19980904; EP 98944779 A 19980904; JP 2000510735 A 19980904