EP 1015591 A2 20000705 - IMPROVED METHOD OF PRODUCTION OF PNEUMOCOCCAL SURFACE PROTEINS
Title (en)
IMPROVED METHOD OF PRODUCTION OF PNEUMOCOCCAL SURFACE PROTEINS
Title (de)
VERBESSERTES VERFAHREN ZUR HERSTELLUNG VON PNEUMOCOCCUS-SPEZIFISCHEN OBERFLÄCHENPROTEINEN
Title (fr)
PROCEDE DE PRODUCTION AMELIOREE DE PROTEINES DE SURFACE PNEUMOCOCCIQUES
Publication
Application
Priority
- US 9819740 W 19980918
- US 93298297 A 19970918
Abstract (en)
[origin: WO9914333A2] The present invention provides improved methods for preparation of immunoligical or vaccine compositions comprising PspA-like polypeptides. Specifically, the present invention provides vaccine compositions wherein PspA or PspA-like polypeptide from Rx1 or other representatives of clade 2 or family 1 have been produced by recombinant methods. Recombinant constructs are provided which express a substantially homogeneous, truncated form of immunologically active PspA-like polypeptides in host cells transformed with such constructs.
IPC 1-7
C12N 15/31; C07K 14/315; C12N 1/21; C12N 5/10; C07K 16/12; A61K 39/09; A61K 39/395
IPC 8 full level
C07K 14/315 (2006.01); C12N 1/21 (2006.01); C12N 15/31 (2006.01); A61K 39/00 (2006.01)
CPC (source: EP)
C07K 14/3156 (2013.01); A61K 39/00 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9914333 A2 19990325; WO 9914333 A3 19990603; AU 9574598 A 19990405; CA 2304128 A1 19990325; EP 1015591 A2 20000705
DOCDB simple family (application)
US 9819740 W 19980918; AU 9574598 A 19980918; CA 2304128 A 19980918; EP 98949414 A 19980918