EP 1015623 A1 20000705 - DRUG DISCOVERY USING MULTIPLE MEMBRANE MIMETIC AFFINITIES
Title (en)
DRUG DISCOVERY USING MULTIPLE MEMBRANE MIMETIC AFFINITIES
Title (de)
AUFFINDEN VON MEDIKAMENTEN UNTER VERWENDUNG VON MEHRFACHEN MEMBRANEN MIT MIMETISCHEN AFFINITÄTEN
Title (fr)
PROCEDE DE DECOUVERTE DE MEDICAMENTS FAISANT APPEL AUX AFFINITES MIMETIQUES DE MEMBRANES MULTIPLES
Publication
Application
Priority
- US 9817398 W 19980821
- US 5683397 P 19970822
Abstract (en)
[origin: WO9910522A1] The measurement of multiple membrane affinities of test compounds, methods and compositions useful for acquiring data characteristic of such affinities, and a method and system for using such data alone or in combination with other molecular descriptors for the prediction of biological activity are described. The numerical values characteristic of biologically relevant interaction of test compounds with membrane mimetic surfaces are compared with corresponding values of one or more control compounds having a known biological activity. Probable biological activity of a test compound is identified with those control compounds whose multiple membrane interaction values most closely correlate to those of the test compound.
IPC 1-7
IPC 8 full level
B01J 20/281 (2006.01); C12Q 1/00 (2006.01); G01N 30/88 (2006.01); G01N 33/15 (2006.01); G01N 33/50 (2006.01); G01N 33/543 (2006.01); G01N 30/02 (2006.01); G01N 30/89 (2006.01)
CPC (source: EP)
G01N 33/54306 (2013.01); G01N 33/5432 (2013.01); G01N 33/54373 (2013.01); G01N 30/02 (2013.01); G01N 30/89 (2013.01)
Citation (search report)
See references of WO 9910522A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9910522 A1 19990304; AU 736198 B2 20010726; AU 9201898 A 19990316; CA 2300863 A1 19990304; DE 1015623 T1 20020207; EP 1015623 A1 20000705; ES 2161203 T1 20011201; GR 20010300057 T1 20011031; IL 134458 A0 20010430; JP 2001514375 A 20010911; NO 20000838 D0 20000221; NO 20000838 L 20000330
DOCDB simple family (application)
US 9817398 W 19980821; AU 9201898 A 19980821; CA 2300863 A 19980821; DE 98944484 T 19980821; EP 98944484 A 19980821; ES 98944484 T 19980821; GR 20010300057 T 20011031; IL 13445898 A 19980821; JP 2000507830 A 19980821; NO 20000838 A 20000221