Global Patent Index - EP 1015629 A1

EP 1015629 A1 2000-07-05 - BIOCONJUGATION OF OLIGONUCLEOTIDES

Title (en)

BIOCONJUGATION OF OLIGONUCLEOTIDES

Title (de)

BIOKONJUGATION VON OLIGONUKLEOTIDEN

Title (fr)

BIOCONJUGAISON D'OLIGONUCLEOTIDES

Publication

EP 1015629 A1 (EN)

Application

EP 98903461 A

Priority

  • US 9800589 W
  • US 3465197 P
  • US 5820697 P

Abstract (en)

[origin: WO9830575A1] This invention discloses a novel method for conjugating macromolecules to other molecular entities. Specifically, this invention discloses a method for conjugating or derivatizing macromolecules, such as oligonucleotides and proteins, using cycloaddition reactions, such as the Diels-Alder reaction or 1,3-dipolar cycloadditions. Included in the invention are the novel bioconjugated macromolecules that can be prepared according to the method of the invention.

IPC 1-7 (main, further and additional classification)

C12Q 1/68; C07H 21/02; C12P 19/34

IPC 8 full level (invention and additional information)

C07H 19/067 (2006.01); C07H 19/04 (2006.01); C07H 19/10 (2006.01); C07H 19/20 (2006.01); C07H 21/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C08G 65/329 (2006.01); C08G 85/00 (2006.01); C12N 15/09 (2006.01); C12N 15/113 (2010.01); C12P 19/34 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C12N 15/113 (2013.01); C07H 19/04 (2013.01); C07H 21/00 (2013.01); C12N 2310/351 (2013.01)

Citation (search report)

See references of WO 9830720A1

Designated contracting state (EPC)

AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9830575 A1 19980716; AU 6022798 A 19980803; AU 6240698 A 19980803; AU 747242 B2 20020509; CA 2277159 A1 19980716; CA 2277545 A1 19980716; EP 0968223 A1 20000105; EP 0968223 A4 20071121; EP 0968223 B1 20161221; EP 1015629 A1 20000705; EP 2256133 A1 20101201; EP 2256133 B1 20161214; EP 2319854 A1 20110511; EP 2319854 B1 20161130; EP 2319855 A1 20110511; EP 2319855 B1 20160406; JP 2001508657 A 20010703; JP 2001509828 A 20010724; WO 9830720 A1 19980716

INPADOC legal status


2004-03-17 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030801

2000-07-05 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19990721

2000-07-05 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE