EP 1015629 A1 20000705 - BIOCONJUGATION OF OLIGONUCLEOTIDES
Title (en)
BIOCONJUGATION OF OLIGONUCLEOTIDES
Title (de)
BIOKONJUGATION VON OLIGONUKLEOTIDEN
Title (fr)
BIOCONJUGAISON D'OLIGONUCLEOTIDES
Publication
Application
Priority
- US 9800589 W 19980107
- US 3465197 P 19970108
- US 5820697 P 19970908
Abstract (en)
[origin: WO9830720A1] This invention discloses a novel method for conjugating RNA oligonucleotides with other molecular entities exclusively at the 5'-position of the oligonucleotide. Specifically, this invention discloses a method for conjugating or derivatizing RNA oligonucleotides via transcription in the presence of a 5'-modified guanosine. Included in the invention are the novel bioconjugated oligonucleotides that can be prepared according to the method of the invention.
IPC 1-7
IPC 8 full level
C07H 19/04 (2006.01); C07H 19/067 (2006.01); C07H 19/10 (2006.01); C07H 19/20 (2006.01); C07H 21/00 (2006.01); C07H 21/02 (2006.01); C07H 21/04 (2006.01); C08G 65/329 (2006.01); C08G 85/00 (2006.01); C12N 15/09 (2006.01); C12N 15/11 (2006.01); C12N 15/113 (2010.01); C12P 19/34 (2006.01); C12Q 1/68 (2006.01)
CPC (source: EP)
C07H 19/04 (2013.01); C07H 21/00 (2013.01); C12N 15/113 (2013.01); C12N 2310/351 (2013.01)
Citation (search report)
See references of WO 9830720A1
Designated contracting state (EPC)
AT BE CH DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9830720 A1 19980716; AU 6022798 A 19980803; CA 2277545 A1 19980716; EP 1015629 A1 20000705; JP 2001508657 A 20010703
DOCDB simple family (application)
US 9800589 W 19980107; AU 6022798 A 19980107; CA 2277545 A 19980107; EP 98903461 A 19980107; JP 53123098 A 19980107