EP 1017398 A1 20000712 - PROTEASOME INHIBITORS, UBIQUITIN PATHWAY INHIBITORS OR AGENTS THAT INTERFERE WITH THE ACTIVATION OF NF-KB VIA THE UBIQUITIN PROTEASOME PATHWAY TO TREAT INFLAMMATORY AND AUTOIMMUNE DISEASES
Title (en)
PROTEASOME INHIBITORS, UBIQUITIN PATHWAY INHIBITORS OR AGENTS THAT INTERFERE WITH THE ACTIVATION OF NF-KB VIA THE UBIQUITIN PROTEASOME PATHWAY TO TREAT INFLAMMATORY AND AUTOIMMUNE DISEASES
Title (de)
PROTEASOME INHIBITOREN, INHIBITOREN DES UBIQUITINWEGES ODER VERBINDUNGEN, DIE MIT DER DURCH DEN UBIQUITINWEG ENSTEHENDEN NF-KB AKTIVIERUNG INTERFERIEREN ZUR BEHANDLUNG VON ENTZÜNDLICHEN UND AUTOIMMUNERKRANKUNGEN
Title (fr)
INIHIBITEURS DE PROTEASOME, INHIBITEURS DES VOIES DE L'UBIQUITINE OU AGENTS ENTRAVANT L'ACTIVATION DE NF-$g(k)B PAR LES VOIES DE l'UBIQUITINE PROTEASOME POUR TRAITER DES MALADIES INFLAMMATOIRES ET DES MALADIES AUTOIMMUNES
Publication
Application
Priority
- US 9820065 W 19980925
- US 6103897 P 19970925
- US 6956297 P 19971212
- US 7488798 P 19980217
Abstract (en)
[origin: WO9915183A1] This invention is directed to the treatment of inflammatory and autoimmune diseases by administering proteasome inhibitors, ubiquitin pathway inhibitors, agents that interfere with the activation of NF- kappa B via the ubiquitin proteasome pathway, or mixtures thereof. The invention is further directed to the treatment of inflammatory and autoimmune diseases by administering an effective combination of a glucocorticoid and a proteasome inhibitor, ubiquitin pathway inhibitor, agent that interferes with the activation of NF- kappa B via the ubiquitin proteasome pathway, or mixture thereof. Pharmaceutical compositions comprising a combination of a glucocorticoid and a proteasome inhibitor, ubiquitin pathway inhibitor, agent that interferes with the activation of NF- kappa B via the ubiquitin proteasome pathway, or mixture thereof are also contemplated within the scope of the invention.
IPC 1-7
IPC 8 full level
A61K 45/00 (2006.01); A61K 31/16 (2006.01); A61K 31/407 (2006.01); A61K 31/573 (2006.01); A61K 45/06 (2006.01); A61P 11/06 (2006.01)
CPC (source: EP)
A61K 31/16 (2013.01); A61P 11/06 (2017.12)
Citation (search report)
See references of WO 9915183A1
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9915183 A1 19990401; WO 9915183 A9 19990729; AU 9580098 A 19990412; CA 2304622 A1 19990401; EP 1017398 A1 20000712; JP 2001517631 A 20011009
DOCDB simple family (application)
US 9820065 W 19980925; AU 9580098 A 19980925; CA 2304622 A 19980925; EP 98949490 A 19980925; JP 2000512552 A 19980925