EP 1017694 A2 20000712 - N-5,6,7,8-TETRAHYDRO(1,6)NAPHTHYRIDINE-N'-PHENYLUREA DERIVATIVES
Title (en)
N-5,6,7,8-TETRAHYDRO(1,6)NAPHTHYRIDINE-N'-PHENYLUREA DERIVATIVES
Title (de)
N-5,6,7,8-TETRAHYDRO(1,6)NAPHTHYRIDINE-N'-PHENYLHARNSTOFF DERIVATE
Title (fr)
DERIVES DE LA N-5,6,7,8-TETRAHYDRO(1,6)NAPHTHYRIDINE-N'-PHENYLUREE
Publication
Application
Priority
- EP 9805904 W 19980915
- GB 9720052 A 19970919
Abstract (en)
[origin: WO9915526A2] N-(naphthyridinyl)-N'-phenyl-ureas/thioureas of general formula (I) are useful for the treatment and/or prophylaxis of anxiety, mania, depression, panic disorders and/or aggression, disorders associated with a subarachnoid haemorrhage or neural shock, the effects associated with withdrawal from substances of abuse such as cocaine, nicotine, alcohol and benzodiazepines, disorders treatable and/or preventable with anti-convulsive agents, such as epilepsy including post-traumatic epilepsy, Parkinson's disease, psychosis, migraine, cerebral ischaemia, Alzheimer's disease and other degenerative diseases such as Huntingdon's chorea, schizophrenia, obsessive compulsive disorders (OCD), neurological deficits associated with AIDS, sleep disorders (including circadian rhythm disorders, insomnia and narcolepsy), tics (e.g. Giles de la Tourette's syndrome), traumatic brain injury, tinnitus, neuralgia, especially trigeminal neuralgia, neuropathic pain, dental pain, cancer pain, inappropriate neuronal activity resulting in neurodysthesias in diseases such as diabetes, multiple sclerosis (MS) and motor neurone disease, ataxias, muscular rigidity (spasticity), temporomandibular joint dysfunction, and amyotrophic lateral sclerosis (ALS).
IPC 1-7
IPC 8 full level
A61K 31/4375 (2006.01); A61P 9/00 (2006.01); A61P 25/00 (2006.01); A61P 25/04 (2006.01); A61P 25/06 (2006.01); A61P 25/08 (2006.01); A61P 25/14 (2006.01); A61P 25/16 (2006.01); A61P 25/18 (2006.01); A61P 25/20 (2006.01); A61P 25/22 (2006.01); A61P 25/24 (2006.01); A61P 25/28 (2006.01); A61P 25/30 (2006.01); A61P 43/00 (2006.01); C07D 471/04 (2006.01)
CPC (source: EP)
A61P 9/00 (2017.12); A61P 25/00 (2017.12); A61P 25/04 (2017.12); A61P 25/06 (2017.12); A61P 25/08 (2017.12); A61P 25/14 (2017.12); A61P 25/16 (2017.12); A61P 25/18 (2017.12); A61P 25/20 (2017.12); A61P 25/22 (2017.12); A61P 25/24 (2017.12); A61P 25/28 (2017.12); A61P 25/30 (2017.12); A61P 43/00 (2017.12); C07D 471/04 (2013.01)
Citation (search report)
See references of WO 9915526A2
Designated contracting state (EPC)
BE CH DE ES FR GB IT LI NL
DOCDB simple family (publication)
WO 9915526 A2 19990401; WO 9915526 A3 19990520; CA 2303994 A1 19990401; EP 1017694 A2 20000712; GB 9720052 D0 19971119; JP 2001517668 A 20011009
DOCDB simple family (application)
EP 9805904 W 19980915; CA 2303994 A 19980915; EP 98951421 A 19980915; GB 9720052 A 19970919; JP 2000512831 A 19980915