EP 1017695 A1 20000712 - RESOLUTION OF OPTICALLY-ACTIVE COMPOUNDS
Title (en)
RESOLUTION OF OPTICALLY-ACTIVE COMPOUNDS
Title (de)
TRENNUNG VON OPTISCH AKTIVEN VERBINDUNGEN
Title (fr)
RESOLUTION DE COMPOSES OPTIQUEMENT ACTIFS
Publication
Application
Priority
- AU 9800807 W 19980925
- AU PO944597 A 19970926
- AU PP071397 A 19971203
- AU PP146898 A 19980123
Abstract (en)
[origin: WO9916769A1] Methods for the separation of enantiomers of mianserin or mianserin-like compounds by using (+)- or (-)-di-p-toluoyl-(L) or (D)-tartaric acid. Also claimed are optically pure (+)- or (-)- mianserin-like compounds and pharmaceutical preparations containing these compounds. Additionally methods for treating disturbances of 5-hydroxytrytamine metabolism and histamine metabolism, and treating conditions such as depression, hypertension, congestive heart failure, migraine, anxiety, schizophrenia, gastrointestinal disturbances, diarrhoea, asthma or allergic conditions is also claimed. The mianserin-like compound has formula (1) wherein X = CH2, O, S or NR<4>, and Y = H, CN or (2); Z = O, S or NR<2>.
IPC 1-7
IPC 8 full level
C07D 487/04 (2006.01); C07D 498/04 (2006.01); C07D 513/04 (2006.01)
CPC (source: EP)
C07D 487/04 (2013.01); C07D 513/04 (2013.01)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9916769 A1 19990408; EP 1017695 A1 20000712; EP 1017695 A4 20020116
DOCDB simple family (application)
AU 9800807 W 19980925; EP 98946144 A 19980925