Global patent index - EP 1017818 A2

EP 1017818 A2 2000-07-12 - MACROPHAGE DERIVED CHEMOKINE (MDC), MDC ANALOGS, MDC INHIBITOR SUSTANCES, AND USES THEREOF

Title (en)

MACROPHAGE DERIVED CHEMOKINE (MDC), MDC ANALOGS, MDC INHIBITOR SUSTANCES, AND USES THEREOF

Title (de)

VON MAKROPHAGEN ABSTAMMENDE CHEMOKIN (MDC) UND MDC ANALOGE, MDC INHIBITOREN, UND IHRE VERWENDUNGEN

Title (fr)

CHEMOKINE DERIVEE DE MACROPHAGES (MDC), ANALOGUES DE MDC, SUBSTANCES INHIBITRICES DE MDC ET UTILISATIONS CORRESPONDANTS

Publication

EP 1017818 A2 (EN)

Application

EP 98951961 A

Priority

  • US 9820270 W
  • US 93910797 A
  • US 6744798 A

Abstract (en)

[origin: CA2302806A1] The present invention provides purified and isolated polynucleotide sequences encoding a novel macrophage-derived C-C chemokine designated "Macrophage Derived Chemokine" (MDC), and polypeptide fragments and analogs thereof. Also provided are materials and methods for the recombinant or synthetic production of the chemokine, fragments, and analogs; and purified and isolated chemokine protein, and polypeptide fragments and analogs thereof. Also provided are antibodies reactive with the chemokine and methods of making and using all of the foregoing. Also provided are assays for identifying modulators of MDC chemokine activity.

IPC 1-7 (main, further and additional classification)

C12N 15/19; A61K 38/19; A61K 39/00; A61K 39/395; C07K 14/52; C07K 16/24; C12N 1/19; C12N 1/21; C12N 5/10; C12N 5/18; G01N 33/68

IPC 8 full level (invention and additional information)

A61K 38/19 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 14/52 (2006.01); C07K 16/24 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 5/18 (2006.01); C12N 15/19 (2006.01); G01N 33/68 (2006.01)

IPC 8 main group level (invention and additional information)

C12N (2006.01)

Citation (search report)

See references of WO 9915666A3

Designated contracting state (EPC)

AT BE CH DE ES FR GB IE IT LI SE

EPO simple patent family

AU 760296 B2 20030508; AU 9777898 A 19990412; CA 2302806 A1 19990401; EP 1017818 A2 20000712

INPADOC legal status

2007-02-07 [18D] DEEMED TO BE WITHDRAWN

- Ref Legal Event Code: 18D

- Effective date: 20060720

2006-04-12 [RAP1] TRANSFER OF RIGHTS OF AN EP PUBLISHED APPLICATION

- Owner name: ICOS CORPORATION

- Ref Legal Event Code: RAP1

2004-07-14 [17Q] FIRST EXAMINATION REPORT

- Ref Legal Event Code: 17Q

- Effective date: 20040526

2000-07-12 [17P] REQUEST FOR EXAMINATION FILED

- Ref Legal Event Code: 17P

- Effective date: 20000412

2000-07-12 [AK] DESIGNATED CONTRACTING STATES:

- Ref Legal Event Code: AK

- Designated State(s): AT BE CH DE ES FR GB IE IT LI SE