EP 1017818 A2 20000712 - MACROPHAGE DERIVED CHEMOKINE (MDC), MDC ANALOGS, MDC INHIBITOR SUSTANCES, AND USES THEREOF
Title (en)
MACROPHAGE DERIVED CHEMOKINE (MDC), MDC ANALOGS, MDC INHIBITOR SUSTANCES, AND USES THEREOF
Title (de)
VON MAKROPHAGEN ABSTAMMENDE CHEMOKIN (MDC) UND MDC ANALOGE, MDC INHIBITOREN, UND IHRE VERWENDUNGEN
Title (fr)
CHEMOKINE DERIVEE DE MACROPHAGES (MDC), ANALOGUES DE MDC, SUBSTANCES INHIBITRICES DE MDC ET UTILISATIONS CORRESPONDANTS
Publication
Application
Priority
- US 9820270 W 19980928
- US 93910797 A 19970926
- US 6744798 A 19980428
Abstract (en)
[origin: CA2302806A1] The present invention provides purified and isolated polynucleotide sequences encoding a novel macrophage-derived C-C chemokine designated "Macrophage Derived Chemokine" (MDC), and polypeptide fragments and analogs thereof. Also provided are materials and methods for the recombinant or synthetic production of the chemokine, fragments, and analogs; and purified and isolated chemokine protein, and polypeptide fragments and analogs thereof. Also provided are antibodies reactive with the chemokine and methods of making and using all of the foregoing. Also provided are assays for identifying modulators of MDC chemokine activity.
IPC 1-7
C12N 15/19; C07K 14/52; A61K 38/19; C07K 16/24; G01N 33/68; C12N 5/18; C12N 1/21; C12N 1/19; C12N 5/10; A61K 39/395; A61K 39/00
IPC 8 full level
A61K 38/19 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 14/52 (2006.01); C07K 16/24 (2006.01); C12N 1/19 (2006.01); C12N 1/21 (2006.01); C12N 5/10 (2006.01); C12N 5/18 (2006.01); C12N 15/19 (2006.01); G01N 33/68 (2006.01)
IPC 8 main group level
C12N (2006.01)
Citation (search report)
See references of WO 9915666A2
Designated contracting state (EPC)
AT BE CH DE ES FR GB IE IT LI SE
DOCDB simple family (publication)
AU 760296 B2 20030508; AU 9777898 A 19990412; CA 2302806 A1 19990401; EP 1017818 A2 20000712
DOCDB simple family (application)
AU 9777898 A 19980928; CA 2302806 A 19980928; EP 98951961 A 19980928