Global Patent Index - EP 1017851 A1

EP 1017851 A1 2000-07-12 - ALLELIC VARIANTS OF THE PHOSPHOLIPASE C-$g(g)1 GENE ASSOCIATED WITH BIPOLAR DISORDER

Title (en)

ALLELIC VARIANTS OF THE PHOSPHOLIPASE C-$g(g)1 GENE ASSOCIATED WITH BIPOLAR DISORDER

Title (de)

ALLELISCHE VARIANTEN DES PHOSPHOLIPASE C-GAMMA 1-GENS, DAS MIT BIPOLARER ERKRANKUNG EINHERGEHT

Title (fr)

ALLELES DU GENE PHOSPHOLIPASE C-$g(g)1 ASSOCIE AU TROUBLE BIPOLAIRE

Publication

EP 1017851 A1 (EN)

Application

EP 98946199 A

Priority

  • CA 9800940 W
  • CA 2216686 A

Abstract (en)

[origin: WO9915697A1] The present invention relates to the use of phospholipase C- gamma 1 gene for the diagnosis, prognosis and development of treatments of bipolar disorder and/or lithium response. There is provided a method for the identification of patient with susceptibility to bipolar disorder and/or lithium response, which comprises the steps of: a) obtaining a nucleic acid sample of the patient; and b) determining allelic variants of phospholipase C- gamma 1 gene present in the sample, and wherein certain allelic variants are indicative of a risk of pipolar disorder and/or lithium response.

IPC 1-7 (main, further and additional classification)

C12Q 1/68; A01K 67/027; C12N 5/10

IPC 8 full level (invention and additional information)

A01K 67/027 (2006.01); C12N 5/10 (2006.01); C12N 9/20 (2006.01); C12N 15/09 (2006.01); C12Q 1/68 (2006.01)

CPC (invention and additional information)

C12Q 1/6883 (2013.01); C12N 9/20 (2013.01); A01K 2217/05 (2013.01); A01K 2217/075 (2013.01); C12Q 2600/156 (2013.01)

Citation (search report)

See references of WO 9915697A1

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9915697 A1 19990401; AU 9335498 A 19990412; CA 2216686 A1 19990324; EP 1017851 A1 20000712; JP 2001517457 A 20011009

INPADOC legal status


2002-11-27 [18W] WITHDRAWN

- Date of withdrawal: 20020927

2000-07-12 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 20000405

2000-07-12 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE