Title (en)

Quinolinecarboxylic acid derivatives

Title (de)

Chinolincarbonsäurederivate

Title (fr)

Dérivés d'acide carboxylique

Publication

EP 1018513 A3 20040721 (EN)

Application

EP 99123695 A 19950518

Priority

• EP 95918742 A 19950518
• JP 10317794 A 19940518

Abstract (en)

[origin: EP0710662A1] A quinolinecarboxylic acid represented by general formula (C) or a medicinally acceptable salt thereof, each having a serotonergic receptor-stimulating effect on sertonin 4 receptors. In said formula, C represents hydroxymethyl, methoxy, ethoxy or morpholinyl. Therefore they have the effect of activating digestive motion and are efficacious in ameliorating chronic gastritis, diabetes and various diseases accompanying the lowering of stomach motility and gastric excretory function after gastrectomy, such as heartburn, anorexia, epigastralgia and abdominal swelling, and in treating reflux esophagitis, false ileus and constipation. <CHEM>

IPC 1-7

C07D 451/06

IPC 8 full level

C07D 215/54 (2006.01); A61K 31/47 (2006.01); A61K 31/535 (2006.01); A61P 1/00 (2006.01); A61P 43/00 (2006.01); C07D 401/06 (2006.01); C07D 451/04 (2006.01); C07D 451/06 (2006.01); C07D 451/12 (2006.01)

CPC (source: EP KR US)

A61P 1/00 (2017.12 - EP); A61P 1/14 (2017.12 - EP); A61P 43/00 (2017.12 - EP); C07D 451/04 (2013.01 - EP KR US); C07D 451/12 (2013.01 - EP US)

Citation (search report)

• [X] MARIA L. IZQUIERDO ET AL.: "Synthesis and structural, conformational and pharmacological study of N-beta(or gamma)acyloxyalkylnortropinones", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY., vol. 24, no. 2, 1989, EDITIONS SCIENTIFIQUE ELSEVIER, PARIS., FR, pages 123 - 129, XP002252544, ISSN: 0223-5234
• [X] CHEMICAL ABSTRACTS, vol. 109, no. 3, 18 July 1988, Columbus, Ohio, US; abstract no. 22817t, GUTKOWSKA, BOZENNA ET AL.: "Synthesis of some amide derivatives of 3-amino-tropane with expected pharmaclogical activity.II." XP002252545 & ACTA POL. PHARM., vol. 43, no. 6, 1986, pages 553 - 558 & DATABASE CAPLUS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002252547
• [X] CHEMICAL ABSTRACTS, vol. 106, no. 23, 8 June 1987, Columbus, Ohio, US; abstract no. 195780s, ARIAS, M.S. ET AL.: "Conformational study of N-substituted 8-azabicyclo[3.2.1]octan-3-ones" XP002252546 & J. MOL: STRUCT:, vol. 147, no. 3-4, 1986, pages 381 - 388 & DATABASE CAPLUS CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; XP002252548

Designated contracting state (EPC)

AT BE CH DE DK ES FR GB GR IE IT LI LU MC NL PT SE

DOCDB simple family (publication)

EP 0710662 A1 19960508; EP 0710662 A4 19960918; EP 0710662 B1 20010404; AT E200286 T1 20010415; AT E316970 T1 20060215; AU 2454895 A 19951205; AU 685632 B2 19980122; CA 2167055 A1 19951123; DE 69520545 D1 20010510; DE 69520545 T2 20010809; DE 69534768 D1 20060413; DE 69534768 T2 20070201; DK 1018513 T3 20060403; EP 1018513 A2 20000712; EP 1018513 A3 20040721; EP 1018513 B1 20060201; ES 2252907 T3 20060516; JP 3829879 B2 20061004; JP H0834784 A 19960206; KR 960703907 A 19960831; US 5753673 A 19980519; WO 9531455 A1 19951123

DOCDB simple family (application)

EP 95918742 A 19950518; AT 95918742 T 19950518; AT 99123695 T 19950518; AU 2454895 A 19950518; CA 2167055 A 19950518; DE 69520545 T 19950518; DE 69534768 T 19950518; DK 99123695 T 19950518; EP 99123695 A 19950518; ES 99123695 T 19950518; JP 11879495 A 19950517; JP 9500954 W 19950518; KR 19960700086 A 19960109; US 57853296 A 19960118