Global Patent Index - EP 1019046 A1

EP 1019046 A1 2000-07-19 - PROTEASE INHIBITORS

Title (en)

PROTEASE INHIBITORS

Title (de)

PROTEASEINHIBITOREN

Title (fr)

INHIBITEURS DE PROTEASES

Publication

EP 1019046 A1 (EN)

Application

EP 98920926 A

Priority

  • US 9808740 W
  • US 4506797 P

Abstract (en)

[origin: WO9848799A1] The present invention provides compounds of formula (I) which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia or malignancy; and metabolic bone disease therewith.

IPC 1-7 (main, further and additional classification)

A61K 31/41; A61K 31/415; A61K 31/42; A61K 31/425; A61K 31/495; A61K 31/50; A61K 31/505; A61K 31/53; A61K 31/555; C07D 231/04; C07D 231/06; C07D 231/10; C07D 233/02; C07D 233/04; C07D 233/54; C07D 233/96; C07D 237/00; C07D 237/02; C07D 239/02; C07D 241/02; C07D 249/08; C07D 251/00; C07D 253/00; C07D 257/08; C07D 257/12

IPC 8 full level (invention and additional information)

C12N 9/50 (2006.01); A61K 31/421 (2006.01); A61K 31/426 (2006.01); A61K 31/427 (2006.01); A61K 31/4375 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/4709 (2006.01); A61K 31/4725 (2006.01); A61K 31/5377 (2006.01); A61K 38/00 (2006.01); A61P 1/02 (2006.01); A61P 19/00 (2006.01); A61P 19/02 (2006.01); A61P 43/00 (2006.01); C07D 233/90 (2006.01); C07D 263/34 (2006.01); C07D 277/20 (2006.01); C07D 277/56 (2006.01); C07D 401/12 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07K 5/078 (2006.01)

CPC (invention and additional information)

C07D 417/12 (2013.01); C07D 277/56 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07K 5/06139 (2013.01)

Designated contracting state (EPC)

AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

EPO simple patent family

WO 9848799 A1 19981105; AR 012622 A1 20001108; AU 7365198 A 19981124; BR 9809333 A 20000704; CA 2287989 A1 19981105; CN 1261276 A 20000726; CO 4940477 A1 20000724; EP 1019046 A1 20000719; EP 1019046 A4 20021127; HU 0001294 A2 20010428; HU 0001294 A3 20010628; IL 132629 D0 20010319; JP 2002504097 A 20020205; KR 20010020391 A 20010315; MA 26487 A1 20041220; NO 995268 A 19991115; NO 995268 D0 19991028; PE 69099 A1 19990926; PL 337725 A1 20000828; TR 9902703 T2 20000221; ZA 9803522 B 19981029

INPADOC legal status


2003-07-30 [18D] DEEMED TO BE WITHDRAWN

- Effective date: 20030104

2002-11-27 [A4] SUPPLEMENTARY SEARCH REPORT

- Effective date: 20021014

2002-11-27 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A4

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-07-19 [17P] REQUEST FOR EXAMINATION FILED

- Effective date: 19991117

2000-07-19 [AK] DESIGNATED CONTRACTING STATES:

- Kind Code of Ref Document: A1

- Designated State(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE

2000-07-19 [AX] REQUEST FOR EXTENSION OF THE EUROPEAN PATENT TO

- Free text: SI PAYMENT 19991117