EP 1019046 A4 20021127 - PROTEASE INHIBITORS
Title (en)
PROTEASE INHIBITORS
Title (de)
PROTEASEINHIBITOREN
Title (fr)
INHIBITEURS DE PROTEASES
Publication
Application
Priority
- US 9808740 W 19980429
- US 4506797 P 19970429
Abstract (en)
[origin: WO9848799A1] The present invention provides compounds of formula (I) which inhibit proteases, including cathepsin K, pharmaceutical compositions of such compounds, and methods for treating diseases of excessive bone loss or cartilage or matrix degradation, including osteoporosis; gingival disease including gingivitis and periodontitis; arthritis, more specifically, osteoarthritis and rheumatoid arthritis; Paget's disease; hypercalcemia or malignancy; and metabolic bone disease therewith.
IPC 1-7
A61K 31/41; A61K 31/415; A61K 31/42; A61K 31/425; A61K 31/495; A61K 31/50; A61K 31/505; A61K 31/53; A61K 31/555; C07D 231/04; C07D 231/06; C07D 231/10; C07D 233/02; C07D 233/04; C07D 233/54; C07D 233/96; C07D 237/00; C07D 237/02; C07D 239/02; C07D 241/02; C07D 249/08; C07D 251/00; C07D 253/00; C07D 257/08; C07D 257/12
IPC 8 full level
A61K 31/421 (2006.01); A61K 31/426 (2006.01); A61K 31/427 (2006.01); A61K 31/4375 (2006.01); A61K 31/4439 (2006.01); A61K 31/454 (2006.01); A61K 31/4709 (2006.01); A61K 31/4725 (2006.01); A61K 31/5377 (2006.01); A61K 38/00 (2006.01); A61P 1/02 (2006.01); A61P 19/00 (2006.01); A61P 19/02 (2006.01); A61P 43/00 (2006.01); C07D 233/90 (2006.01); C07D 263/34 (2006.01); C07D 277/20 (2006.01); C07D 277/56 (2006.01); C07D 401/12 (2006.01); C07D 413/12 (2006.01); C07D 413/14 (2006.01); C07D 417/12 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07K 5/078 (2006.01); C12N 9/50 (2006.01)
CPC (source: EP KR)
A61K 31/41 (2013.01 - KR); A61P 1/02 (2018.01 - EP); A61P 19/00 (2018.01 - EP); A61P 19/02 (2018.01 - EP); A61P 43/00 (2018.01 - EP); C07D 277/56 (2013.01 - EP); C07D 417/12 (2013.01 - EP); C07D 417/14 (2013.01 - EP); C07D 471/04 (2013.01 - EP); C07K 5/06139 (2013.01 - EP)
Citation (search report)
No further relevant documents disclosed
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9848799 A1 19981105; AR 012622 A1 20001108; AU 7365198 A 19981124; BR 9809333 A 20000704; CA 2287989 A1 19981105; CN 1261276 A 20000726; CO 4940477 A1 20000724; EP 1019046 A1 20000719; EP 1019046 A4 20021127; HU P0001294 A2 20010428; HU P0001294 A3 20010628; IL 132629 A0 20010319; JP 2002504097 A 20020205; KR 20010020391 A 20010315; MA 26487 A1 20041220; NO 995268 D0 19991028; NO 995268 L 19991115; PE 69099 A1 19990926; PL 337725 A1 20000828; TR 199902703 T2 20000221; ZA 983522 B 19981029
DOCDB simple family (application)
US 9808740 W 19980429; AR P980101999 A 19980429; AU 7365198 A 19980429; BR 9809333 A 19980429; CA 2287989 A 19980429; CN 98806641 A 19980429; CO 98023491 A 19980429; EP 98920926 A 19980429; HU P0001294 A 19980429; IL 13262998 A 19980429; JP 54738998 A 19980429; KR 19997010013 A 19991029; MA 25047 A 19980424; NO 995268 A 19991028; PE 00032098 A 19980427; PL 33772598 A 19980429; TR 9902703 T 19980429; ZA 983522 A 19980428