EP 1019063 A1 20000719 - MODULATION OF IMMUNE RESPONSES
Title (en)
MODULATION OF IMMUNE RESPONSES
Title (de)
MODULATION DER IMMUNREAKTION
Title (fr)
MODULATION DE REACTIONS IMMUNITAIRES
Publication
Application
Priority
- US 9819126 W 19980916
- ZA 978319 A 19970916
Abstract (en)
[origin: WO9913885A1] A method of affecting or modulating for stimulation or suppression of the immune cell product pursuant to an immune response to an external or endogenous immune stimulant in an animal comprising the steps of administering to such animal a non-toxic immune modulating effective quantity of a compound selected from the group consisting of compounds of the general chemical formula (I) R1-CO-NR2R3 wherein R1 is selected from the group consisting of H and lower (i.e. C1 to C3) alkyl and C2 to C3 alkenyl groups; R2 and R3 are the same or different and each is selected from the group consisting of H, lower (i.e. C1 to C3) alkyl and C2 to C3 alkenyl groups which may optionally be halogenated or hydroxylated, or which may in combination with one another from a -(CH2)n- group wherein n is any number from 2 to 5, or the group -(CH2)2-O-(CH2)2 and metabolites and prodrugs thereof. The method is useful in the treatment of a variety of ailments associated with inappropriate immune responses and the invention provides for the use of compounds of Formula (I) in the manufacture of medicaments for use in the treatment of such ailments and for pharmaceutical preparations containing same.
IPC 1-7
IPC 8 full level
A61K 31/16 (2006.01); A61K 31/00 (2006.01); A61P 11/02 (2006.01); A61P 11/06 (2006.01); A61P 13/12 (2006.01); A61P 17/06 (2006.01); A61P 27/16 (2006.01); A61P 29/00 (2006.01); A61P 37/02 (2006.01); A61P 37/08 (2006.01); A61P 43/00 (2006.01)
CPC (source: EP)
A61K 31/00 (2013.01); A61P 11/02 (2017.12); A61P 11/06 (2017.12); A61P 13/12 (2017.12); A61P 17/06 (2017.12); A61P 27/16 (2017.12); A61P 29/00 (2017.12); A61P 37/02 (2017.12); A61P 37/08 (2017.12); A61P 43/00 (2017.12)
Designated contracting state (EPC)
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE
DOCDB simple family (publication)
WO 9913885 A1 19990325; AU 737867 B2 20010906; AU 9389098 A 19990405; BR 9812321 A 20000905; CA 2304119 A1 19990325; CN 1279612 A 20010110; EP 1019063 A1 20000719; EP 1019063 A4 20030903; IL 135091 A0 20010520; JP 2001516721 A 20011002; NO 20001341 D0 20000315; NO 20001341 L 20000516; NZ 503418 A 20010223
DOCDB simple family (application)
US 9819126 W 19980916; AU 9389098 A 19980916; BR 9812321 A 19980916; CA 2304119 A 19980916; CN 98810397 A 19980916; EP 98946998 A 19980916; IL 13509198 A 19980916; JP 2000511505 A 19980916; NO 20001341 A 20000315; NZ 50341898 A 19980916